Turk Kardiyol Dern Ars. 2020; 48(4): 410-424 | DOI: 10.5543/tkda.2020.03374
Traditional Chinese medicine practices used in COVID-19 (Sars-cov 2/Coronavirus-19) treatment in clinic and their effects on the cardiovascular system
, Miraç Ekici1
, Zinar Alan1
, Elif Özbir Elevli1
, Aysenur Yaman Bucak2
, Nuerbiye Aobuliaikemu3
, Ali Yağız Üresin21
Department of Pharmaceutical Botany, Istanbul University Faculty of Pharmacy, İstanbul, Turkey2
Department of Medical Pharmacology, Istanbul University Faculty of Medicine, İstanbul, Turkey3
Department of Pharmacognosy, İstanbul University Faculty of Pharmacy, İstanbul, Turkey
OBJECTIVE The aim of this study was to evaluate the effectiveness of plants used in the formulations of traditional Chinese medicine (TCM), which were also used in clinical trials to treat patients with the novel coronavirus COVID-19, and to assess their effects on the cardiovascular system.
METHODS A literature review of PubMed, ResearchGate, ScienceDirect, the Cochrane Library, and TCM monographs was conducted and the effects of the plants on the cardiovascular system and the mechanisms of action in COVID-19 treatment were evaluated.
RESULTS The mechanism of action, cardiovascular effects, and possible toxicity of 10 plants frequently found in TCM formulations that were used in the clinical treatment of COVID-19 were examined.
CONCLUSION TCM formulations that had been originally developed for earlier viral diseases have been used in COVID-19 treatment. Despite the effectiveness seen in laboratory and animal studies with the most commonly used plants in these formulations, the clinical studies are currently insufficient according to standard operating procedures. More clinical studies are needed to understand the safe clinical use of traditional plants.
Antiviral, cardiovascular system; COVID-19; immunomodulator; traditional Chinese medicine.
How to cite this article
Emine Akalın, Miraç Ekici, Zinar Alan, Elif Özbir Elevli, Aysenur Yaman Bucak, Nuerbiye Aobuliaikemu, Ali Yağız Üresin. Traditional Chinese medicine practices used in COVID-19 (Sars-cov 2/Coronavirus-19) treatment in clinic and their effects on the cardiovascular system. Turk Kardiyol Dern Ars. 2020; 48(4): 410-424
Corresponding Author: Emine Akalın, Türkiye