EDITORIAL COMMENT | |
1. | What is new in the European Society of Cardiology 2014 update on myocardial revascularization guidelines? Aylin Yıldırır PMID: 25655843 doi: 10.5543/tkda.2015.27612 Pages 1 - 6 Abstract | |
2. | Acute Pulmonary Embolism Diagnosis and Treatment Guidelines (ESC 2014) Leyla Elif Sade PMID: 25655844 doi: 10.5543/tkda.2015.73780 Pages 7 - 11 Abstract | |
3. | Highlights from the 2014 European Society of Cardiology Guidelines for Aortic Diseases Musluhittin Emre Erkuş, Recep Demirbağ PMID: 25655845 doi: 10.5543/tkda.2015.15943 Pages 12 - 17 Abstract | |
ORIGINAL ARTICLE | |
4. | The relationship between neutrophil to lymphocyte ratio and blood pressure variability in hypertensive and normotensive subjecs Barış Kılıçaslan, Hüseyin Dursun, Sermin Kaymak, Mehmet Aydın, Cenk Ekmekçi, İbrahim Susam, Öner Özdoğan PMID: 25655846 doi: 10.5543/tkda.2015.10594 Pages 18 - 24 Objectives: Blood pressure (BP) variability is associated with hypertensive (HT) target organ damage and cardiovascular events. The aim of this study was to investigate the relation between neutrophil to lymphocyte ratio (NLR) and BP variabil- ity in hypertensive and normotensive subjects. Study design: In this cross-sectional study, 150 subjects (63 male, mean age 52.1±5.2 years) were enrolled. In all patients, blood samples and 24-hour ambulatory blood pressure (BP) monitoring were obtained. According to 24-hour ambulatory BP results, participants were divided into four investigation categories. Group 1= Normotensive dipper (ND), Group 2= Normotensive non-dipper (NN), Group 3= HT dipper (HD), Group 4= HT non-dipper (HN). Results: Highest NLR values were determined in the HN group (p=0.005 vs. ND, p=0.046 vs. NN and p<0.01 vs. HD). NLR values were similar among the ND, NN and HD groups (p>0.05, for all). NLR was correlated with night systolic blood pressure (SBP) (r=0.178, p=0.031), night diastolic blood pressure (DBP) (r=0.176, p=0.032) and BP variation rate (r=- 0.246, p=0.003). Multiple linear regression analysis showed BP variation rate to be an independent predictor of high NLR value (β=0.186, 95% CI=0.918-0.982, p=0.044). In ROC anal- ysis, a level of NLR>2.7 predicted non-dipper HT with 83% sensitivity and 65% specificity (ROC area under curve: 0.653, 95% CI=0.565-0.741, p=0.001). Conclusion: In the present study, we found that NLR levels were significantly correlated with BP variability. The measure- ment of NLR may be used to indicate increased risk of HT- related adverse cardiovascular events. |
5. | Pericardial effusion predicts mortality in patients with chronic obstructive pulmonary disease Can Yücel Karabay, Gokhan Gol, Arzu Kalayci, Alev Kilicgedik, Merve Ciftci, Hakan Gunen PMID: 25655847 doi: 10.5543/tkda.2015.27109 Pages 25 - 30 Objectives: Chronic obstructive pulmonary disease (COPD) is an increasingly important cause of morbidity and mortality worldwide. Pericardial effusion (PE) is a current issue proven to be a mortality predictor, especially in pulmonary arterial hypertension. In this study, we aimed to evaluate the prognostic value of PE in COPD. Study design: The study cohort consisted of 488 COPD patients and a control group of 50 healthy patients. At the start of the study, 37 patients (7.5%) had PE. Mean followup time was 12 months (range; 1-16 months). Clinical spirometric and echocardiographic data were compared between patients with PE(+) group (n=37), patients without PE(–) group (n=451) and the healthy control group. Results: Right ventricular functions were more depressed and pulmonary arterial pressure was more elevated in the PE(+) group. Also, Kaplan-Meier survival curve analysis showed that at one-year follow- up, mortality was higher in the PE(+) group: PE(-) group 139 (30.8%), PE(+) group 21 (56.8%) log-Rank p value: 0.009). Age, presence of PE, and oxygen usage were independent predictors of mortality in Cox regression analysis. Conclusion: Presence of PE predicts mortality in COPD patients at one-year follow-up. |
6. | The morphologic and functional features of LAD myocardial bridging at multi detector computed tomography coronary angiography: correlation with coronary artery disease Alper Aydın, Rahmi Çubuk, Mehmet Mahir Atasoy, Tayfun Gürol, Ozer Soylu, Bahadır Dağdeviren PMID: 25655848 doi: 10.5543/tkda.2015.23672 Pages 31 - 37 Objectives: The aim of this study was to retrospectively evaluate the morphologic and functional features of myocardial bridging (MB) and to investigate the impact of morphologic features on presence of atherosclerosis with multi-detector computed tomography (MDCT) coronary angiography. Study design: The study population consisted of 191 consecutive patients. Besides coronary lesions, morphologic features of the MB (depth, length and the distance of the tunneled artery from the left coronary ostium) were analyzed. Results: MDCT detected MB on left anterior descending artery in 41 patients (21.5%). The prevalence of atherosclerotic plaques proximal to the MB of LAD was 49% (20/41). There was a statistically significant correlation between percentage of systolic compression and depth of the tunneled segment (r=0.538, p<0.01). There was no relation between distance of the tunneled segment from the ostium and degree of systolic compression. No significant correlation was found between percentage of systolic compression and length of the tunneled segment (r=0.058, p=0.721). Morphologic features of MB were not related to the presence of CAD in proximal segments. Conclusion: MDCT coronary angiography depicts the morphologic and functional features of the MB in detail. The depth of MB segment was correlated with systolic compression of MB. There was no relationship between distance of the tunneled segment from the ostium and systolic compression. |
7. | Prevention of recurrent cryptogenic stroke with percutaneous closure of patent foramen ovale; one year follow-up study with magnetic resonance imaging and Holter monitoring Ahmet Hakan Ateş, Hamza Sunman, Kudret Aytemir, Hikmet Yorgun, Uğur Canpolat, Mehmet Akif Topcuoğlu, Kader Karlı Oğuz, Levent Şahiner, Ergün Barış Kaya, Lale Tokgözoğlu, Giray Kabakçı, Ali Oto PMID: 25655849 doi: 10.5543/tkda.2015.68148 Pages 38 - 46 Objectives: In this study, we aimed to evaluate the effect of percutaneous closure of patent foramen ovale (PFO) on the recurrence of stroke and new cardiac arrhythmia using magnetic resonance imaging (MRI) and Holter monitoring. Study design: Patients with PFO had >1 previous stroke or transient ischemic attack documented with MRI in the first event. PFO with right to left shunt was detected by transesophageal echocardiography (TEE) and transcranial Doppler ultrasound. MRI examinations were performed on patients before and one year after PFO closure was applied. A twenty-four hour Holter monitoring was performed in all patients within 1 month before and 6 months after the procedure. Results: Percutaneous PFO closure was performed on 47 patients (25 female, mean age: 38.7 years) who had cerebral ischemic events detected by MRI. A year after the procedure, TEE showed that there was no residual interatrial right-to-left shunting. After a 14 month follow-up, no new cerebrovascular event and no new lesion on MRI were recorded. The incidence of arrhythmia did not increase significantly after the procedure on Holter monitoring (p=0.917). Conclusion: One-year clinical and MRI follow-up study of patients with cerebral ischemic events and percutaneous closure of PFO showed no recurrent event and no significant complication associated with the procedure. In addition, Holter monitorization demonstrated that the procedure did not increase the incidence of arrhythmias compared with pre-procedural monitoring. |
EDITORIAL COMMENT | |
8. | Should we close PFO? Hakan Güllü PMID: 25655850 doi: 10.5543/tkda.2015.91471 Pages 47 - 48 Abstract | |
ORIGINAL ARTICLE | |
9. | Left ventricle geometry affects coronary flow reserve in diabetic patients Gülhan Yüksel Kalkan, Mustafa Gur, Zafer Elbasan, Ahmet Oytun Baykan, Osman Kuloğlu, Durmuş Yıldıray Şahin, Taner Şeker, Filiz Ekşi Haydardedeoğlu, Ömer Şen, Hakan Uçar, Sinan Kırım, Murat Çaylı PMID: 25655851 doi: 10.5543/tkda.2015.59432 Pages 49 - 57 Objectives: The aim of this study was to investigate the association between coronary flow reserve (CFR) and left ventricle (LV) geometric patterns in patients with newly-diagnosed diabetes mellitus (DM). Study design: We studied 116 patients with newly-diagnosed DM and 31 healthy control subjects. Echocardiographic examination was performed on all subjects. Four different geometric patterns were identified in diabetic patients, according to LV mass index (LVMI) and relative wall thickness (RWT) [NG: Normal geometry; CR: Concentric remodeling; EH: Eccentric hypertrophy; CH: Concentric hypertrophy]. CFR was calculated as the hyperemic to resting coronary diastolic peak velocities ratio. Results: Compared with controls, CFR was decreased in diabetic patients (p<0.05). The lowest CFR values were observed in the CH group compared with control and other groups (p<0.05, for all). Also, CFR values of the CR and EH groups were lower than NG and the control group (p<0.05, for all). CFR was associated with LV geometry (r=-0.449, p=0.001), LVMI (r=-0.401, p<0.001), RWT (r=-0.247, p=0.008), HbA1c (r=-0.576, p<0.001) and mitral valve E/A ratio (r=0.239, p=0.01) in bivariate analysis. CFR was independently associated with LV geometry (β=-0.449, p<0.001), LVMI (β=-0.192, p=0.016), and HbA1c (β=-0.576, p<0.001) in multivariate analysis. Conclusion: CFR was impaired in newly-diagnosed DM. The degree of this deformation increases from normal geometry towards to concentric hypertrophy. This condition suggests that myocardial structural remodeling due to diabetes might be effective on CFR. |
EDITORIAL COMMENT | |
10. | Left ventricular remodeling impacts coronary flow reserve in diabetic patients: what is the mechanism? Bahar Pirat PMID: 25655852 doi: 10.5543/tkda.2015.93604 Pages 58 - 59 Abstract | |
ORIGINAL ARTICLE | |
11. | Evaluation of atrial fibrillation (AF) management and cardiovascular risk profile in AF patients: data from Turkish patients in the international observational cross-sectional REALISE AF trial Erdem Diker, Gokmen Bellur, Nurten Yildiz, Cemil Izgi, Lisa Naditch-brûlé PMID: 25655853 doi: 10.5543/tkda.2015.93530 Pages 60 - 74 Objectives: To assess control of atrial fibrillation (AF) and cardiovascular (CV) risk profile of AF patients with previously established AF therapies. Study design: A total of 510 patients (mean (SD) age, 67.1 (12.3) years, 55.1% females) enrolled from 40 centers across Turkey were evaluated on a single-visit basis in terms of patient demographics, characteristics of underlying AF, the frequency and scoring of symptoms according to European Heart Rhythm Association AF cardiac symptoms classification, control of AF, cardiovascular (CV) risk profile, AF treatment and the consistency of current therapeutic practice with evidence-based guidelines. Results: AF was controlled in 39.4% of patients based on sinus rhythm on the day of visit (10.2%) and AF with HR ≤80 bpm (29.2%). Permanent AF was the most commonly identified type of AF (56.0%). Symptoms were evident in 89.2% of patients either before V0 (78.8%) or at V0 (56.5%). Age (72.4%) and hypertension (70.0%) were the leading CV risk factors. Rate-control and rhythm-control strategies were chosen in 76.5 and 19.2% of patients at the enrollment visit. Mean (SD) of EQ-5D scores for VAS and for single index utility were 63.1 (19.8) and 0.62 (0.4), respectively. Conclusion: In this real life survey of AF patients from Turkey participating in the global contemporary, international, observational, cross-sectional REALISE AF survey, AF was determined to be not optimally controlled, leading patients to experience frequent symptoms, functional impairment and altered QoL,as well as frequent hospital admissions for cardiovascular events and a high requirement for procedures. |
CASE REPORT | |
12. | Double cardiac pseudoaneurysm in a postoperative patient Tahereh Davarpasand, Ali Hosseinsabet PMID: 25655854 doi: 10.5543/tkda.2015.06777 Pages 75 - 77 A mitral-aortic intervalvular fibrosa pseudoaneurysm is a rare complication after aortic and mitral valve replacement and aortic root replacement. A left ventricular pseudoaneurysm after mitral valve replacement is also a rare complication. Here, we describe a 48-year-old woman with a history of a Bentall operation and mitral valve replacement 6 years before, presenting with double pseudoaneurysms in the left ventricle and mitral-aortic intervalvular fibrosa, detected via transesophageal echocardiography. |
13. | Dasatinib-induced pulmonary hypertension in acute lymphoblastic leukemia: case report Gülten Taçoy, Atiye Çengel, Zübeyde Nur Özkurt, Sedat Türkoğlu PMID: 25655855 doi: 10.5543/tkda.2015.41763 Pages 78 - 81 Pulmonary hypertension (PHT) is a pathological condition determined as an increase in mean pulmonary arterial pressure ≥25 mmHg. Pulmonary arterial hypertension (PAH) is precapillary PHT and a life-threatening disease group which consists of different etiologies with the same pathological and clinical findings, and which is characterized by elevated pulmonary vascular resistance. Dasatinib is a dual Src/Abl kinase inhibitor associated with higher affinity for BCR/ABL kinase than imatinib, and is used in the treatment of chronic myelocytic leukemia and Philadelphia chromosome positive acute lymphoblastic leukemia (ALL). We describe a case with ALL, in whom dasatinib treatment induced PAH, and who recovered with bosentan treatment. |
14. | Successful transvenous lead extraction using the Evolution System in a 17-kg child Yakup Ergül, İsa Özyılmaz, Alper Güzeltaş, Hasan Tahsin Tola PMID: 25655856 doi: 10.5543/tkda.2015.65188 Pages 82 - 85 Despite technological advancements in the field of pacemaker lead extraction, available data on pediatric patients is limited, and risk of failure and severe complications remains high. In this report, we present the case of a male patient who, at five months old, had been transvenously implanted with a single-chamber ventricular pacemaker due to complete atrioventricular block. At 7-year of age, the patient was referred to us with growth-related lead tension, severe tricuspid insufficiency, and weak battery. We extracted the lead using the Evolution System and replaced the unit with a dual-chamber pacemaker with a SelectSecure lead. This new system can be used for lead extraction even in lowweight pediatric patients with congenital heart disease. Using a thin, lumenless SelectSecure lead appears to reduce the risk of venous obstruction. |
15. | An uncommon localization of a giant hydatid cyst presenting with cardiac tamponade İrfan Şahin, Berk Özkaynak, Burak Ayça, Ertuğrul Okuyan PMID: 25655857 doi: 10.5543/tkda.2015.59207 Pages 86 - 88 Cardiac involvement in hydatid cyst disease is a rare manifestation and may remain asymptomatic for years. The location of the cyst determines the presentation. In this report, we present a case of hydatid cyst presenting with massive pericardial effusion, right ventricle compression leading to cardiac tamponade. The diagnosis was established with transthoracic, transesophageal echocardiagraphy and computed tomography. |
16. | Implantation of a biventricular ICD in a patient with dextrocardia with situs inversus Veysel Kutay Vurgun, Demet Menekşe Gerede, Ali Timuçin Altın, Başar Candemir, Ömer Akyürek PMID: 25655858 doi: 10.5543/tkda.2015.05435 Pages 89 - 92 In order to reduce sudden cardiac death and heart failure symptoms, biventricular implantable cardioverter defibrillator (ICD) implantation is a treatment method commonly used in selected patients with cardiomyopathy. The frequency of dextrocardia in congenital heart defects is approximately 0.4/10000. In this group, the frequency of cardiomyopathy development is rare. In this case report we present a patient with dextrocardia undergoing implantation of biventricular ICD. |
17. | Dislodgement of coronary stent due to rupture of stent balloon Burak Ayça, Ertuğrul Okuyan, İrfan Şahin, Mustafa Hakan Dinçkal PMID: 25655859 doi: 10.5543/tkda.2015.02761 Pages 93 - 94 Rare stent complications, including dislodgement of stent, unexpanded stent, stent fracture and stent loss etc. can occur during percutaneous coronary interventions (PCI). We present a semi-expanded and dislodged stent due to rupture of stent balloon during primary PCI in this case report. An interventional cardiologist should be aware of the possibility of rare complications, such as in this case, and have enough experience and knowledge to handle them. |
INVITED REVIEW | |
18. | Heart transplantation: preoperative evaluation, perioperative management, postoperative follow-up Tahir Yağdı, Sanem Nalbantgil, Mustafa Özbaran PMID: 25655860 doi: 10.5543/tkda.2015.27628 Pages 95 - 108 Heart transplantation has, over the years, become the best treatment choice for patients with end-stage heart failure. The increase in longer waiting times among patients awaiting transplantation is due to scarcity of suitable donor organs. Major improvements in recipient and donor selection, perioperative management and postoperative follow- up such as immunosuppressive treatment and prevention of opportunistic infections have considerably enhanced the outcome of heart transplantation. This review will focus on the managements of these complex patients, as well as |
HOW TO? | |
19. | How to assess pulmonary hypertension with echocardiography? Serpil Eroğlu PMID: 25655861 doi: 10.5543/tkda.2015.91657 Pages 109 - 116 Abstract | |
CASE IMAGE | |
20. | Endomyopericardial metastasis from laryngeal cancer Sabahattin Gündüz, Ertuğrul Zencirci PMID: 25655862 doi: 10.5543/tkda.2015.25488 Page 117 |
21. | Non-invasive estimation of pericardial effusion volume by three-dimensional speckle-tracking echocardiography (From the MAGYAR-Path Study) Attila Nemes, Péter Domsik, Anita Kalapos, Tamás Forster PMID: 25655863 doi: 10.5543/tkda.2015.20165 Page 118 Abstract | |
22. | Multiple cardiac myxomas originating in mitral apparatus Hakan Erkan, Gülhanım Kırış, Gülay Uzun Hekimoğlu PMID: 25655864 doi: 10.5543/tkda.2015.93720 Page 119 |
23. | Removal of broken lead in the extraction process using the FlexCath steerable sheath; a new technique Mehmet Emin Kalkan, Uğur Arslantaş, Mustafa Akçakoyun, Serdar Demir PMID: 25655865 doi: 10.5543/tkda.2015.69337 Page 120 |
24. | Constrictive pericarditis in catheterization laboratory Göknur Tekin PMID: 25655866 doi: 10.5543/tkda.2015.38658 Page 121 |
OTHER ARTICLES | |
25. | Comment on cardiology publications Ertan Ural Page 122 Abstract | |
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