Pericardial effusion predicts mortality in patients with chronic obstructive pulmonary disease [Turk Kardiyol Dern Ars]
Turk Kardiyol Dern Ars. 2015; 43(1): 25-30 | DOI: 10.5543/tkda.2015.27109

Pericardial effusion predicts mortality in patients with chronic obstructive pulmonary disease

Can Yücel Karabay1, Gokhan Gol1, Arzu Kalayci2, Alev Kilicgedik2, Merve Ciftci1, Hakan Gunen1
1Sureyyapaşa Chest & Chest Surgery Education And Research Hospital, Department of Cardiology, ıstanbul
2Koşuyolu Heart Training and Research Hospital, Department of Cardiology, Istanbul, Turkey


OBJECTIVES
Chronic obstructive pulmonary disease (COPD) is an increasingly important cause of morbidity and mortality worldwide. Pericardial effusion (PE) is a current issue proven to be a mortality predictor, especially in pulmonary arterial hypertension. In this study, we aimed to evaluate the prognostic value of PE in COPD.

STUDY DESIGN
The study cohort consisted of 488 COPD patients and a control group of 50 healthy patients. At the start of the study, 37 patients (7.5%) had PE. Mean followup time was 12 months (range; 1-16 months). Clinical spirometric and echocardiographic data were compared between patients with PE(+) group (n=37), patients without PE(–) group (n=451) and the healthy control group.

RESULTS
Right ventricular functions were more depressed and pulmonary arterial pressure was more elevated in the PE(+) group. Also, Kaplan-Meier survival curve analysis showed that at one-year follow- up, mortality was higher in the PE(+) group: PE(-) group 139 (30.8%), PE(+) group 21 (56.8%) log-Rank p value: 0.009). Age, presence of PE, and oxygen usage were independent predictors of mortality in Cox regression analysis.

CONCLUSION
Presence of PE predicts mortality in COPD patients at one-year follow-up.

Keywords: Pulmonary disease, chronic obstructive, pericardial effusion; mortality, predictors

How to cite this article
Can Yücel Karabay, Gokhan Gol, Arzu Kalayci, Alev Kilicgedik, Merve Ciftci, Hakan Gunen. Pericardial effusion predicts mortality in patients with chronic obstructive pulmonary disease. Turk Kardiyol Dern Ars. 2015; 43(1): 25-30

Corresponding Author: Can Yücel Karabay, Türkiye
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