ISSN 1016-5169 | E-ISSN 1308-4488
Archives of the Turkish Society of Cardiology
Homocysteine and Cardiovascular Disease [Turk Kardiyol Dern Ars]
Turk Kardiyol Dern Ars. 2001; 29(3): 181-190

Homocysteine and Cardiovascular Disease

Murat SUCU1, A. Aziz KARADEDE1, Nizamettin TOPRAK1

Homocysteine is a sulphur-containing aınino acid formed during the ınetabolisın of ınethionine . It is ınetabolised by reınethy lation or transsulphuration. Fasting normal ranges are 5- ı 5 ııınoi/L in the general population. Plasma hoınoc yste ine ı eve l s are strongly influenced by diet, as well as genetic factors. It is suggested that atherogenic propensity associated with h yperhoınocysteineın i a results from endothelial dysfunction and injury. Although there is considerable epideın i ologica l evidence for a relation between plasına hoınocyste ine and cardiovascular disease, not all prospective studies have supported such a relationship. Moreover, despite the potential for reducing hoınocysteine levels with increased intake of folic acid, it is not known whether reduction of plasına hoınocyste ine by diet and/or vitamin therapy wi ll reduce cardiovascular disease risk. Hoınocysteine leveıs of mo re than ı 5 ıım oi/L ınay be ınanaged with 400 ııg folate with or without other B vitamins.

Keywords: Homocysteine, cardiovascular disease

How to cite this article
Murat SUCU, A. Aziz KARADEDE, Nizamettin TOPRAK. Homocysteine and Cardiovascular Disease. Turk Kardiyol Dern Ars. 2001; 29(3): 181-190
Manuscript Language: Turkish

Journal Metrics

Journal Citation Indicator: 0.18
CiteScore: 1.1
Source Normalized Impact
per Paper:
SCImago Journal Rank: 0.348

Quick Search

Copyright © 2024 Archives of the Turkish Society of Cardiology

Kare Publishing is a subsidiary of Kare Media.