ISSN 1016-5169 | E-ISSN 1308-4488
Archives of the Turkish Society of Cardiology
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Our Initial Experiences on Intracoronary Pressure and Myocardial Fractional Flow Reserve Measurements in Intermediate Lesions [Turk Kardiyol Dern Ars]
Turk Kardiyol Dern Ars. 2000; 28(5): 306-313

Our Initial Experiences on Intracoronary Pressure and Myocardial Fractional Flow Reserve Measurements in Intermediate Lesions

Murat ÖZDEMİR1, Timur TİMURKAYNAK1, Mustafa CEMRİ1, Bülent BOYACI1, Rıdvan YALÇIN1, Atiye ÇENGEL1, Övsev DÖRTLEMEZ1, Halis DÖRTLEMEZ1

In this article, we tried to summarize our first clinical experience with the measurement of myocardial fractional flow reserve (mFFR) utilising intracoronary pressure recordings in coronary stenoses of intermediate severity. A total of 35 angiographically intermediate lesions (%30-70 stenosis) in 31 patients were evaluated by mFFR. Micromanometer-tipped pressure wire was used to measure intracoronary pressures, and maximum coronary hyperemia was induced by intracoronary adenosine. Isolated intermediate lesions in 2 separate coronary arteries in 4 patients and in a single coronary artery in the remaining 27 patients were evaluated by mFFR. Of the 35 lesions, 29 were de novo and 6 were in-stent stenoses. The mean diameter stenosis with coronary angiography was 49.7 ± 10.1 % and the corresponding mean mFFR was 0.83 ± 0.1. Myocardial fractional flow reserve was found to be below 0.75 in 4(11 %) and 0.75 or above in 31(89%) of the lesions. In those cases in whom mFFR was measured both before and after coronary intervention, the low preprocedural mFFR was observed to increase following a successful procedure. In all cases, high quality intracoronary pressure signals were obtained and no complications were observed with regard to both the manipulation of the 0.014 inch pressure wire and intracoronary adenosine injection. It is concluded that measurement of mFFR in coronary stenoses of intermediate severity with the use of intracoronary pressure recordings obtained through 0.0 14 inch pressure wire during maximum coronary hyperemia induced by intracoronary adenosine injection is a practical and safe technique.

Keywords: Fractional flow reserve, coronary stenosis, intracoronary pressure

How to cite this article
Murat ÖZDEMİR, Timur TİMURKAYNAK, Mustafa CEMRİ, Bülent BOYACI, Rıdvan YALÇIN, Atiye ÇENGEL, Övsev DÖRTLEMEZ, Halis DÖRTLEMEZ. Our Initial Experiences on Intracoronary Pressure and Myocardial Fractional Flow Reserve Measurements in Intermediate Lesions. Turk Kardiyol Dern Ars. 2000; 28(5): 306-313
Manuscript Language: Turkish


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