ISSN 1016-5169 | E-ISSN 1308-4488
Brugada phenocopies: Current evidence, diagnostic algorithms and a perspective for the future [Turk Kardiyol Dern Ars]
Turk Kardiyol Dern Ars. 2020; 48(2): 158-166 | DOI: 10.5543/tkda.2020.06118

Brugada phenocopies: Current evidence, diagnostic algorithms and a perspective for the future

Göksel Çinier1, Gary Tse2, Adrian Baranchuk3
1Department of Cardiology, Kaçkar State Hospital, Rize, Turkey
2Tianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular disease, Department of Cardiology, Tianjin Institute of Cardiology, Second Hospital of Tianjin Medical University, Tianjin, China; Xiamen Cardiovascular Hospital, Xiamen University, Xiamen, China
3Division of Cardiology, Kingston General Hospital, Queen’s University, Canada

Brugada syndrome (BrS) is a congenital channelopathy associated with the development of malignant ventricular arrhythmias and sudden cardiac death. The diagnosis of BrS is made based on Brugada ECG pattern and clinical history. Brugada phenocopies (BrP) are clinical entities that are characterized by ECG patterns identical to those of BrS but arise from different underlying conditions such as metabolic abnormalities, myocardial ischemia and mechanical compression. Distinction between the two is important because BrS requires investigations for risk stratification whereas BrP requires appropriate treatment for the underlying conditions. In the present review, we summarized the current data in the literature, systematic diagnostic approach, gaps in the literature and future perspective on BrP.

Keywords: Brugada phenocopy, Brugada syndrome; electrocardiography.

Corresponding Author: Göksel Çinier, Türkiye
Manuscript Language: English
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