Effect of prognostic nutritional index on short-term survival after transcatheter aortic valve implantation [Turk Kardiyol Dern Ars]
Turk Kardiyol Dern Ars. Ahead of Print: TKDA-97709 | DOI: 10.5543/tkda.2020.97709

Effect of prognostic nutritional index on short-term survival after transcatheter aortic valve implantation

Cafer Panç, Emre Yılmaz, İsmail Gürbak, Fatih Uzun, Mehmet Ertürk
Istanbul Health Sciences University, Mehmet Akif Ersoy Cardiovascular and Thoracic Surgery Training and Research Hospital, Istanbul


INTRODUCTION
Transcatheter aortic valve implantation (TAVI) is a good alternative to surgical aortic valve replacement (SAVR) in patients who are at intermediate, high-risk or unsuitable for SAVR in severe aortic stenosis cases. TAVI is mostly performed elderly patients and although conventional risk scores include a lot of comorbidities, they do not contain functional decline specific to elderly patients. Prognostic nutritional index (PNI), which is a simple and effective parameter for both nutritional and inflammatory status, reflects functional decline in elder people. The aim of the study is to determine the effect of PNI on short-term survival after TAVI.

METHODS
We evaluated the PNI value of 302 patients who underwent TAVI. The study population was divided into two groups according to a cutoff value of PNI: PNI > 43.37 (n = 213; 70%) and PNI < 43.37 (n = 89; 30%).

RESULTS
Patients with lower PNI had significantly higher mortality rates at 30-day period than patients with higher PNI levels (3.3% vs. 31.5%; p < 0.001). Major vascular complications, and cardiac tamponade were found to be significantly higher in the lower PNI group. The cut-off value of PNI for a 30-day survival was 43.37 with 94.3% specificity and 73.4% sensitivity and negative predictive value of PNI was 96.7%. PNI was found to be an independent risk factor for 30-day mortality after TAVI.

CONCLUSION
The higher levels of PNI were associated with short-term survival and decreased post-TAVI complications.

Keywords: prognostic nutritional index, aortic stenosis, transcatheter aortic valve implantation

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Corresponding Author: Cafer Panç, Türkiye
© Copyright 2020 Archives of the Turkish Society of Cardiology
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