ISSN 1016-5169 | E-ISSN 1308-4488
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Use of TIMI Risk Index as a Simple and Valuable Prognostic Tool in Patients with ST-Segment Elevation Myocardial Infarction Who Underwent Primary Percutaneous Coronary Intervention [Turk Kardiyol Dern Ars]
Turk Kardiyol Dern Ars. 2022; 50(3): 192-201 | DOI: 10.5543/tkda.2022.21143

Use of TIMI Risk Index as a Simple and Valuable Prognostic Tool in Patients with ST-Segment Elevation Myocardial Infarction Who Underwent Primary Percutaneous Coronary Intervention

İdris Buğra Çerik1, Ahmet Kaya2, Seçkin Dereli2, Fatih Akkaya2, Mustafa Yenerçağ2, Osman Bektaş2
1Department of Cardiology, Cumhuriyet University School of Medicine, Sivas, Turkey
2Department of Cardiology, Ordu University Training and Research Hospital, Ordu, Turkey


OBJECTIVE
Thrombolysis in Myocardial Infarction Risk Index is a risk stratification model developed to determine the prognosis in ST-segment elevation myocardial infarction patients who underwent fibrinolytic therapy. The information on the effectiveness of Thrombolysis in Myocardial Infarction Risk Index in patients who underwent primary percutaneous coronary intervention is limited. This study aimed to demonstrate the predictive value of Thrombolysis in Myocardial Infarction Risk Index on clinical outcomes in patients presenting with ST-segment elevation myocardial infarction and subsequently undergoing primary percutaneous coronary intervention.

METHODS
A total of 963 patients who presented with ST-segment elevation myocardial infarction and subsequently underwent primary percutaneous coronary intervention were reviewed retrospectively. The discriminative power of Thrombolysis in Myocardial Infarction Risk Index for each outcome of congestive heart failure, death, stroke, and myocardial infarction within 1 month and 1 year after admission was assessed.

RESULTS
Congestive heart failure, death, stroke, and myocardial infarction, and the major adverse cardiac events, which is the composite outcome thereof, were higher in the patient groups with high Thrombolysis in Myocardial Infarction Risk Index values (P <.05). Thrombolysis in Myocardial Infarction Risk Index was an independent predictor of the following outcomes: 1-month survival rate [odds ratio: 1.054 (1.036-1.073)], 1-year survival rate [odds ratio: 1.048 (1.031-1.065)], hospitalization rate due to congestive heart failure within 1 month [odds ratio: 1.041(1.026-1.057)], and within 1 year [odds ratio: 1.040 (1.024-1.055)]. The Thrombolysis in Myocardial Infarction Risk Index level was found to have good discriminative power for 1-month mortality and 1-year mortality rates (Thrombolysis in Myocardial Infarction Risk Index: 22.76, C-statistic: 0.71-0.68, respectively).

CONCLUSION
The results of this study indicated that Thrombolysis in Myocardial Infarction Risk Index value is an independent predictor of clinical outcomes such as death and heart failure but not subsequent myocardial infarction in ST-segment elevation myocardial infarction patients. The use of Thrombolysis in Myocardial Infarction Risk Index can be considered in ST-segment elevation myocardial infarction patients who underwent primary percutaneous coronary intervention as it is an easily applicable and important indicator of prognosis.

Keywords: TIMI risk index, ST-elevation myocardial infarction, prognosis

How to cite this article
İdris Buğra Çerik, Ahmet Kaya, Seçkin Dereli, Fatih Akkaya, Mustafa Yenerçağ, Osman Bektaş. Use of TIMI Risk Index as a Simple and Valuable Prognostic Tool in Patients with ST-Segment Elevation Myocardial Infarction Who Underwent Primary Percutaneous Coronary Intervention. Turk Kardiyol Dern Ars. 2022; 50(3): 192-201

Corresponding Author: İdris Buğra Çerik
Manuscript Language: English


Journal Metrics

Journal Citation Indicator: 0.18
CiteScore: 1.1
Source Normalized Impact
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0.22
SCImago Journal Rank: 0.348

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