Relation of QT Dispersion with Left Ventricular Anatomy in Hemodialysis Patients [Turk Kardiyol Dern Ars]
Turk Kardiyol Dern Ars. 2000; 28(7): 417-421

Relation of QT Dispersion with Left Ventricular Anatomy in Hemodialysis Patients

Tufan TÜKEK1, Vakur AKKAYA1, Alaattin YILDIZ2, Doç Şeref DEMİREL1, Ahmet Bilge SÖZEN1, Hasan KUDAT1, Dursun ATILGAN1, Mustafa ÖZCAN1, Özen GÜVEN1, Ferruh KORKUT1
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Ischemic heart disease, ventricular arhythmia and congestive heart failure are major causes of mortality in hemodialysis patients (HDp). The difference between QT intervals measured from surface ECG (QT dispersion) has been found to be associated with fatal arhythmias in various cardiac diseases. In this case-control study, 35 HDp and 31 healthy controls were investigated for correctedmaximum (QTcmax) and minimum (QTcmin) QT durations, their difference; QT dispersion (QTcd) and their correlation with left ventricular dimensions. Mean time spent on dialysis was 32 (14 months. Corrected QT max (448 ± 40 vs 394 ± 22msec, p<0.0001), QTc min (389 ± 36 vs 359 ± 25msec, p<0.0001) and QTcd (59 ± 14 vs 34 ± 7msec, p<0.0001) were significantly prolonged in HDp compared with controls. ln HDp, QTcmax was correlated with interventricular septum thickness (r=0.46, p=0.007), LV posterior wall thickness (r=0.45, p=0.009) and LV mass index (r=0.48, p=0.004). QTcd was correlated with LV posterior wall thickness (r=0.37, p=0.03), interventricular septum thickness (r=0.47, p=0.005), and wall/cavity ratio (r=0.43, p=0.01), but not with LV mass index (r=0.26, p=0.13). In conclusion, QTcmax, QTcmin and QTcd was found to be increased in HDp compared to controls. Increase in QTcd which is a marker of inhomogeneity in repolarisation, was related with wall thickness directly, and was more associated with the degree of uremic cardiomyopathy.

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How to cite this article
Tufan TÜKEK, Vakur AKKAYA, Alaattin YILDIZ, Doç Şeref DEMİREL, Ahmet Bilge SÖZEN, Hasan KUDAT, Dursun ATILGAN, Mustafa ÖZCAN, Özen GÜVEN, Ferruh KORKUT. Relation of QT Dispersion with Left Ventricular Anatomy in Hemodialysis Patients. Turk Kardiyol Dern Ars. 2000; 28(7): 417-421
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