We investigated usefulness and accuracy of a simplified formula derived from the parameters obtained by proximal isovelocity surface are (PISA) method. The study group consisted of 41(28F, 13M) patients with a mean age of 32.2±7.8 years. All patients had non-calcified mitral stenosis and were being evaluated for timing and type of cardiac interventions. 16 patients had mild aortic regurgitation, 9 patients had mild mitral regurgitation. Of 41 patients 18 were in atrial fibrillation and the rest of them had normal sinus rhythm. The standard PISA method was applied. Mitral valve area (MV A) was calculated by the simplified formula for each patient. Assumption of funnel angle by non-calcified mitral leaflets was empirically considered as 118 degrees. 118/180=0.65 (Constant for angle correction), 2?=6.28, Constant va - lue(C)=0.65x6.28=4.1 MV A= 4.1 xA Vxr2/MV Assessment of MV A by standard PISA formula was compared with the pessure half time (PHT) and planimetry (PLN) methods. Concerning valve areas there were significantly positive correlations between the results of simplified PISA formula and the standard method. PISA(C) vs PHT r=0.85, PISA(C) vs PLN r=0.85, PISA(C) vs PISA r=0.96. As a conclusion the simplified formula provides acceptable agreement between standard PISA and other well known methods. Thus, this formula is recommended for routine clinical practice in assessment of mitral valve area esrimation in patients with non-calcified mitral stenosis
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