Turk Kardiyol Dern Ars. 2016; 44(6): 498-502 | DOI: 10.5543/tkda.2016.65171
Cardiac evaluation in children with hemangiomas
, Faik Sarıalioğlu21
Department Of Pediatric Cardiology, Baskent University, Ankara, Turkey2
Department Of Pediatric Oncology, Baskent University, Ankara, Turkey
OBJECTIVE Hemangiomas are tumors most commonly encountered in pediatric patients, and are frequently treated with propranolol. However, there are currently no standard methods for evaluating cardiac function in patients prior to propranolol treatment. The present study was designed to aid in the evaluation of pretreatment cardiac and effects of propranolol on vital signs in pediatric hemangioma patients.
METHODS A pediatric oncology specialist and a pediatric cardiology specialist examined all patients prior to initiation of propranolol treatment. All patients were examined by the same 2 physicians. Cardiac evaluation included complete echocardiogram and electrocardiography. From September 2009 to January 2014, 146 patients aged 4 days to 10 years were screened.
RESULTS No patient had cardiac contraindication to propranolol. The effect of hemangioma on left ventricle size was examined, but left ventricle dilatation was found in only 3 patients. However, 68 patients had abnormal echocardiogram: 17 had patent foramen ovale, 4 had ventricular septal defect, 9 had atrial septal defect (associated with right heart enlargement), 8 had patent ductus arteriosus, 6 had physiologic pulmonary stenosis, and 1 had an aortic coarctation. No contraindications to propranolol or side effects were observed. However, cardiac anatomic defects were more common in this patient group than in the general population.
CONCLUSION Hemangiomas in infants or children, even in small or premature infants, can be treated with propranolol without significant cardiac side effects. In addition, large dermal hemangiomas were not found to affect ventricular size in pediatric patients.
Cardiovascular parameters, hemangioma, infant, propranolol.
How to cite this article
İlkay Erdoğan, Faik Sarıalioğlu. Cardiac evaluation in children with hemangiomas. Turk Kardiyol Dern Ars. 2016; 44(6): 498-502
Corresponding Author: İlkay Erdoğan, Türkiye