ISSN 1016-5169 | E-ISSN 1308-4488
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The relationship between the QT interval and autonomous and anthropometric features [Turk Kardiyol Dern Ars]
Turk Kardiyol Dern Ars. 2007; 35(4): 216-226

The relationship between the QT interval and autonomous and anthropometric features

Tolga Doğru1, Serdar Günaydın2, Vedat Şimşek1, Murat Tulmaç1, Mahmut Güneri1
1Department Of Cardiology, University Of Kirikkale, Kirikkale, Turkey
2Department Of Cardiovascular Surgery, University Of Kirikkale, Kirikkale, Turkey


OBJECTIVES
We investigated the effect of anthropometric and autonomous factors on the QT interval in both sexes.

STUDY DESIGN
The study included 237 individuals (114 males, 123 females) who were asymptomatic and had no abnormal laboratory or physical findings. The mean age was 47 years (range 20 to 79 years) for men, and 39 years (range 20 to 71 years) for women. All the participants were subjected to a careful history taking, physical examination, routine biochemical examinations, electrocardiographic recording, 24-hour Holter monitoring, and when necessary, color Doppler echocardiography and treadmill exercise test. Serum estrogen levels, serum free and total testosterone levels were also measured in males.

RESULTS
The minimum QT interval was significantly lower in males (p=0.043). The mean QT (p=0.022) and QTc (p<0.001) intervals in females, and QT dispersion in males (p=0.025) were significantly higher. In male participants, the maximum QT interval (p=0.049) and QT dispersion (p=0.043) were significantly different between age groups of 20-44 years and 45-69 years. Parasympathetic activity played a determinant role in the mean and maximum QT intervals. Anthropometric features were not correlated with the QT interval in females, whereas in males, waist-hip ratio was positively correlated with the mean QT and minimum QTc intervals (r=0.188, p=0.049 and r=0.236, p=0.013, respectively). Serum sex hormone levels were significantly effective on the QT interval in males.

CONCLUSION
Concerning anthropometric and autonomic factors, the QT interval is significantly influenced by gender-related features.

Keywords: Anthropometry, arrhythmia, autonomic nervous system, electrocardiography; heart rate; obesity; sex characteristics

Corresponding Author: Tolga Doğru, Türkiye
Manuscript Language: Turkish
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