ISSN 1016-5169 | E-ISSN 1308-4488
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Variation of Computed Tomography-Derived Fractional Flow Reserve Related to Different Vessel Morphology [Turk Kardiyol Dern Ars]
Turk Kardiyol Dern Ars. 2023; 51(6): 419-423 | DOI: 10.5543/tkda.2023.60930

Variation of Computed Tomography-Derived Fractional Flow Reserve Related to Different Vessel Morphology

Toshimitsu Tsugu1, Kaoru Tanaka1, Yuji Nagatomo2, Michel De Maeseneer1, Johan De Mey1
1Department of Radiology, Universitair Ziekenhuis Brussel, Brussels, Belgium
2Department of Cardiology, National Defense Medical College Hospital, Tokorozawa, Japan

A total of 1492 outpatients with suspected coronary artery disease and who underwent computed tomography-derived fractional flow reserve analysis were examined. To investigate the effects of vessel morphology such as lumen diameter or volume on computed tomography-derived fractional flow reserve, nearly the same or subthreshold values affecting computed tomography-derived fractional flow reserve hemodynamics vessels were compared. Case 1 and 2 present almost the same vessel length (case 1 vs. case 2; 135.0 mm vs. 133.6 mm), low-attenuation plaque volume (0 mm3 vs. 0 mm3), intermediate attenuation plaque volume (12.5 mm3 vs. 35.5 mm3), and calcified plaque volume (4.7 mm3 vs. 0 mm3) in the right coronary artery. However, lumen volume (877.8 mm3 vs. 2443.7 mm3) and distal computed tomography-derived fractional flow reserve (0.79 vs. 0.96) were markedly different between the 2 patients. Computed tomography-derived fractional flow reserve depends not only on vessel length or plaque characteristics but also on lumen volume or vessel morphology.

Keywords: FFR, FFRCT, luminal volume, plaque, vessel length

How to cite this article
Toshimitsu Tsugu, Kaoru Tanaka, Yuji Nagatomo, Michel De Maeseneer, Johan De Mey. Variation of Computed Tomography-Derived Fractional Flow Reserve Related to Different Vessel Morphology. Turk Kardiyol Dern Ars. 2023; 51(6): 419-423

Corresponding Author: Toshimitsu Tsugu, Belgium
Manuscript Language: English


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