Glucose Tolerance and Insulin Resistance in Non-obese, Non-diabetic Hypertensives [Turk Kardiyol Dern Ars]
Turk Kardiyol Dern Ars. 1995; 23(1): 15-20

Glucose Tolerance and Insulin Resistance in Non-obese, Non-diabetic Hypertensives

Melek ULUÇAM1, Atiye ÇENGEL1, Nuri ÇAKIR1, Mehmet METİN1, Övsev DÖRTLEMEZ1, Halis DÖRTLEMEZ1

Relations of resistance to insulin-stimulated glucose uptake, secondary hyperinsulinemia, high blood pressure, abnormalities of lipoprotein metabolism and atherosclerotic coronary heart disease are interesting topics of medical investigations. The purpose of this study was to compare nondiabetic nonobese hypertensive with normotensive cases who were also neither diabetic nor nonobese from the point of tissue insulin resistance, triglyceride (TG) and cholesterol levels. Oral glucose tolerance test (OGTT), an indirect method for determining insulin resistance, was used in this study. The major finding of our study was that fasting insulin levels of hypertensives (11.1±5.5 µU/ml) were significantly greater than normotensives (7.8±4.1 µU/ml). This was considered to be related to insulin resistance. Another finding was that prevalence of impaired OGTT is 33% in the hypertensive study group.

Keywords: Hypertension, insulin resistance, hyperinsulinemia

How to cite this article
Melek ULUÇAM, Atiye ÇENGEL, Nuri ÇAKIR, Mehmet METİN, Övsev DÖRTLEMEZ, Halis DÖRTLEMEZ. Glucose Tolerance and Insulin Resistance in Non-obese, Non-diabetic Hypertensives. Turk Kardiyol Dern Ars. 1995; 23(1): 15-20
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