Double Valve Replacement in a Patient With Hb S-Beta Thalassemia

Open heart surgery in patients with hemoglobinopathies have been reported rarely. These patients present potential management problems during the intraoperative and postoperative period. Cardiopulmonary bypass causes some unavoidable hemolysis, platelet destruction, acidosis and protein denaturation. We report a cases presenting with Hb S-beta thalassemia who underwent replacement of the aortic and mitral valves with Medtronic prostheses and tricuspid annuloplasty without serious complications as a result of appropriate perioperative management.