Perceived stress level is associated with coronary artery disease severity in patients with ST segment elevation myocardial infarction [Turk Kardiyol Dern Ars]
Turk Kardiyol Dern Ars. Ahead of Print: TKDA-30020 | DOI: 10.5543/tkda.2020.30020

Perceived stress level is associated with coronary artery disease severity in patients with ST segment elevation myocardial infarction

Serkan Kahraman1, Fatma Cam Kahraman2, Hicaz Zencirkiran Agus1, Ali Kemal Kalkan1, Fatih Uzun1, Muammer Karakayalı1, Mehmet altunova1, Samet Sevnc1, Ali Riza Demir1, Emre Yilmaz1, Mehmet Erturk1
1University of Health Sciences, Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Center, Training and Research Hospital, Department of Cardiology, Istanbul, TURKEY
2Istanbul Bilim University, Faculty of Arts and Sciences, Department of Psychology, Istanbul, Turkey


OBJECTIVE
Stress is known as a significant risk factor for coronary atherosclerosis and adverse cardiovascular events. However, the stress-related coronary atherosclerotic burden has not been investigated yet. In our study, we aimed to investigate the relationship between perceived stress scale (PSS) and Syntax scores in patients with ST segment elevation myocardial infarction (STEMI).


METHODS
Four hundred forty patients with STEMI were prospectively enrolled and divided into two groups according to their PSS levels with a cut-off value of 17.5 by using ROC curve analysis. 361 patients with low PSS level were categorized as group 1 and 79 patients with high PSS level were categorized as group 2.


RESULTS
Syntax score [16.0 (10.0-22.5); 22.5 (15.0-25.5), p<0.001] and Syntax score II [24.8 (19.0-32.6); 30.9 (22.3-38.9), p<0.001] were significantly higher in group 2. Spearman analysis demonstrated that PSS was related with Syntax score (r=0.153, p=0.001) and Syntax score II (r=0.216, p<0.001). Additionally, PSS (OR: 2.434, CI: 1.446-4.096, p=0.001) was found as an independent predictor of moderate to high Syntax score. PSS score of patients with in-hospital mortality was also higher than those without mortality [15 (10-20); 9 (4-16), p=0.007].


CONCLUSION
Stress seems to accelerate coronary atherosclerotic process and burden. The increased stress level was also found to be an independent predictor of high Syntax score.

Keywords: coronary artery disease, perceived stress scale, ST-segment elevation myocardial infarction, Syntax score

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Corresponding Author: Serkan Kahraman, Türkiye
© Copyright 2020 Archives of the Turkish Society of Cardiology
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