Turk Kardiyol Dern Ars. 2002; 30(3): 183-190
Three-Years Experience in Heart Transplantation
, Tahir YAĞDI1
, Sanem NALBANTGİL1
, Mustafa ÖZBARAN1
Several advances have occurred during the past two decades in the management of patients with end-stage heart disease. Cardiac transplantation is the best therapeutic modality to achieve long-term survival for these patients. Cardiac transplantation was performed in 18 patients (13 male and 5 female) during a three-year period. The mean age was 44.7±14.1 years (21-63 years). The etiology was idiopathic dilated cardiomyopathy in 10 patients, and ischemic cardiomyopathy in seven. Orthotopic cardiac transplantation was performed using the biatrial technique. The mean cardiac ischemia time was 170.7±61.7 minutes (101-335 min.). Triple-drug immunosuppression (cyclosporin A, prednisone, azathioprine) was given in all patients. Rejection was monitored by routine endomyocardial biopsy. All patients underwent annual coronary angiography.
RESULTS Perioperative mortality was 11.1% with 2 deaths. Prolonged intubation was needed in 1 patient. Acute renal failure requiring dialysis was seen in 2 patients. One patient died from sepsis, 1 from hemophagocytic syndrome, 2 from aspergillus pneumonia, and 1 from staphylococcus pneumonia. All deaths were doserved within postoperative 6 months. Grade IIIA or greater rejection necessitating treatment was encountered in 7 patients.
CONCLUSION Our preliminary results encourage us to continue transplantation practice. Close monitoring of rejection and infection is necessary in cardiac transplant patients.
How to cite this article
Ahmet HAMULU, Tahir YAĞDI, Sanem NALBANTGİL, Mustafa ÖZBARAN. Three-Years Experience in Heart Transplantation. Turk Kardiyol Dern Ars. 2002; 30(3): 183-190