ISSN 1016-5169 | E-ISSN 1308-4488
pdf
The Relationships Between Chocolate Consumption and Endothelial Dysfunction in Patients with Heart Failure [Turk Kardiyol Dern Ars]
Turk Kardiyol Dern Ars. 2022; 50(5): 334-339 | DOI: 10.5543/tkda.2022.21249

The Relationships Between Chocolate Consumption and Endothelial Dysfunction in Patients with Heart Failure

İbrahim Etem Dural1, Ersel Onrat1, Sefa Çelik2, Ayhan Vurmaz2, Zafer Yalım1, Serkan Gökaslan1, Çiğdem Özer Gökaslan2, Cem Korucu1, Uğur Aksu1
1Department of Cardiology, Afyonkarahisar Health Sciences University, Afyonkarahisar, Turkey
2Department of Biochemistry, Afyonkarahisar Health Sciences University, Afyonkarahisar, Turkey


OBJECTIVE
Dietary recommendations, in addition to medications, have recently become important in the treatment of heart failure. Our study aimed to show the positive effects of both milk chocolate and dark chocolate on heart failure through endothelial functions.


METHODS
Twenty patients with heart failure and reduced ejection fraction were included in the study. In this randomized, crossover study, some of the patients consumed milk chocolate and some consumed dark chocolate. We recorded the patients' 6-minute walking tests, flow-mediated dilatation values, plasma catechin, epicatechin, and N-terminal pro-brain natriuretic peptide values before and after chocolate consumption. After 2 weeks, their chocolate consumption was changed. The same parameters were measured again.


RESULTS
A significant decrease was observed in N-terminal pro-brain natriuretic peptide values after consumption of both milk chocolate (356 ± 54.2 and 310 ± 72.1 pg/mL; P =.007) and dark chocolate (341 ± 57 and 301 ± 60.1 pg/mL;P =.028). Flow-mediated dilation values increased after dark chocolate consumption (8.9 ± 3% and 14 ± 4.5%; P =.019).


CONCLUSION
Chocolate consumption acutely decreases N-terminal pro-brain natriuretic pep-tide values in heart failure. Dark chocolate consumption also seems to improve endothelial functions by increasing flow-mediated dilation values.

Keywords: Heart failure, chocolate, flow-mediated dilation

How to cite this article
İbrahim Etem Dural, Ersel Onrat, Sefa Çelik, Ayhan Vurmaz, Zafer Yalım, Serkan Gökaslan, Çiğdem Özer Gökaslan, Cem Korucu, Uğur Aksu. The Relationships Between Chocolate Consumption and Endothelial Dysfunction in Patients with Heart Failure. Turk Kardiyol Dern Ars. 2022; 50(5): 334-339

Corresponding Author: İbrahim Etem Dural
Manuscript Language: English


Journal Metrics

Journal Citation Indicator: 0.18
CiteScore: 1.1
Source Normalized Impact
per Paper:
0.22
SCImago Journal Rank: 0.348

Quick Search



Copyright © 2024 Archives of the Turkish Society of Cardiology



Kare Publishing is a subsidiary of Kare Media.