Turk Kardiyol Dern Ars. 2019; 47(2): 122-127 | DOI: 10.5543/tkda.2018.11524
Tp-e interval and Tp-e/QT ratio in clinically stable pediatric heart transplant recipients
Serhat Koca1, Feyza Ayşenur Paç1, Sabit Kocabeyoğlu2, Maze Zabun1, Deniz Eriş1, Doğan Emre Sert2, Ümit Kervan2, Mustafa Paç21Department of Pediatric Cardiology, Türkiye Yüksek İhtisas Training and Research Hospital, Ankara, Turkey
2Department of Cardiovascular Surgery, Türkiye Yüksek İhtisas Training and Research Hospital, Ankara, Turkey
Objective: A study of the T wave peak-to-end (Tp-e) interval, the Tp-e/QT ratio, and the Tp-e/QTc ratio in pediatric heart transplant recipients (HTRs), a group which has a higher risk of sudden cardiac death than the normal population, has not previously been reported. The aim of this study was to assess alterations in ventricular repolarization using the Tp–e interval, Tp–e/ QT ratio, and Tp–e/QTc ratio in clinically stable pediatric HTRs.
Methods: A total of 13 clinically stable HTRs, 13 patients who had undergone cardiac surgery (CS) under cardiopulmonary bypass, and 16 healthy controls under 18 years of age were retrospectively evaluated.
Results: No significant differences were observed between the HTR, CS, and control groups in terms of QTc, JTc interval, and T wave amplitude (p>0.05). The Tp-e interval (p=0.001), Tp-e/QT ratio (p<0.001), and Tp-e/QTc ratio (p=0.001) were significantly higher in the HTR group compared with the CS and normal control participants.
Conclusion: The Tp-e interval, Tp-e/QT ratio, and Tp-e/QTc ratio were elevated in stable HTRs compared with the normal and CS groups.
Keywords: Children, dispersion of ventricular repolarization; heart transplantation.
Corresponding Author: Serhat Koca, Türkiye
Manuscript Language: English