Obstructive mechanical mitral valve thrombosis and gastric adenocarcinoma: A therapeutic dilemma [Turk Kardiyol Dern Ars]
Turk Kardiyol Dern Ars. 2020; 48(8): 775-778 | DOI: 10.5543/tkda.2020.09406

Obstructive mechanical mitral valve thrombosis and gastric adenocarcinoma: A therapeutic dilemma

Ekrem Karaayvaz, Zeynep Gizem Demirtakan, Mehmet Rasih Sonsöz, Aslı Nalbant, Zehra Buğra
Department of Cardiology, Istanbul University Istanbul Faculty of Medicine, Istanbul, Turkey

Fibrinolysis is an option for the management of mechanical prosthetic valve thrombosis when surgery has prohibitive risks. Current guidelines suggest recombinant tissue plasminogen activator (not to exceed 100 mg) with unfractionated heparin. A low-dose (25 mg) alteplase regimen as treatment in patients with a high risk of bleeding warrants further research. This report describes the case of a 65-year-old woman with a history of mechanical prosthetic mitral valve replacement who was diagnosed with signet ring cell adenocarcinoma of the stomach and obstructive mechanical prosthetic thrombosis on echocardiogram. Details of challenging aspects of this case and the use of modified fibrinolytic therapy are provided.

Keywords: Echocardiography, fibrinolytic; malignancy; obstructive mechanical prosthetic thrombosis.











How to cite this article
Ekrem Karaayvaz, Zeynep Gizem Demirtakan, Mehmet Rasih Sonsöz, Aslı Nalbant, Zehra Buğra. Obstructive mechanical mitral valve thrombosis and gastric adenocarcinoma: A therapeutic dilemma. Turk Kardiyol Dern Ars. 2020; 48(8): 775-778

Corresponding Author: Zeynep Gizem Demirtakan, Türkiye
© Copyright 2021 Archives of the Turkish Society of Cardiology
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