ISSN 1016-5169 | E-ISSN 1308-4488
A case of ranitidine-induced bradycardia [Turk Kardiyol Dern Ars]
Turk Kardiyol Dern Ars. 2007; 35(4): 242-245

A case of ranitidine-induced bradycardia

Mehmet Uzun1, Ufuk Dizer1, Mehmet Yokuşoğlu2, Mehmet Cem Başel1
1Girne Military Hospital, Girne, Turkey
2Gulhane Military Medical School, Department Of Cardiology, Ankara, Turkey

Ranitidine, a selective histamine-2 antagonist, may seldom cause bradycardia. A 28-year-old male patient was admitted with high fever, nausea, vomiting, headache, and joint tenderness. He was conscious and in good general status. His temperature was 38.4 °C, pulse rate was 84/min, and blood pressure was 100/60 mmHg. He had a history of vasovagal syncope. Treatment was instituted for infection and fever. His temperature became normal on the second day. On the third day, the patient complained of stomach ache. Intravenous ranitidine was administered on the fourth day, after which heart rate decreased to 30/min. His temperature was 36.4 °C and blood pressure was 110/70 mmHg. Electrocardiographic (ECG) monitoring was instituted in the intensive care unit, at which time he was in sinus rhythm with a heart rate of 34/min. During ECG monitoring heart rate ranged from 28/min to 35/min. Upon discontinuation of ranitidine, heart rate returned to normal on the ninth day.

Keywords: Bradycardia/chemically induced, histamine H2 antagonists/adverse effects, ranitidine/adverse effects

How to cite this article
Mehmet Uzun, Ufuk Dizer, Mehmet Yokuşoğlu, Mehmet Cem Başel. A case of ranitidine-induced bradycardia. Turk Kardiyol Dern Ars. 2007; 35(4): 242-245

Corresponding Author: Mehmet Uzun, Türkiye
Manuscript Language: Turkish

Journal Metrics

Journal Citation Indicator: 0.18
CiteScore: 1.1
Source Normalized Impact
per Paper:
SCImago Journal Rank: 0.348

Quick Search

Copyright © 2024 Archives of the Turkish Society of Cardiology

Kare Publishing is a subsidiary of Kare Media.