ISSN 1016-5169 | E-ISSN 1308-4488
Evaluation of aortic elastic properties in patients with systemic sclerosis [Turk Kardiyol Dern Ars]
Turk Kardiyol Dern Ars. 2014; 42(7): 635-642 | DOI: 10.5543/tkda.2014.03162

Evaluation of aortic elastic properties in patients with systemic sclerosis

Özgül Uçar Elalmış1, Hülya Çiçekçioğlu1, Ahmet Karagöz2, Zeynep Özbalkan Aşlar3, Yaşar Karaaslan3
1Department of Cardiology, Ankara Numune Training and Research Hospital, Ankara
2Department of Cardiology, Giresun Prof. Dr. Atilla İlhan Özdemir State Hospital, Giresun
3Department of Rheumatology, Ankara Numune Training and Research Hospital, Ankara

The aim of this study was to investigate the elastic properties of the aorta, which are known to be predictors of cardiovascular morbidity and mortality in patients with systemic sclerosis (SSc).

Forty patients (2 males, 38 females) with SSc who had been referred to echocardiography without any exclusion criteria were enrolled in the study. The control group consisted of 38 subjects (4 males, 34 females) who were examined in the cardiology out-patient clinic and referred to echocardiography for any indication in the same period. Parameters related to diastolic functions of the left ventricle were obtained by echocardiography and the following parameters of aortic elasticity were calculated according to these formulas: aortic strain = ([AOS - AOD]/AOD), aortic stiffness index (β) = ln (systolic blood pressure/diastolic blood pressure)/aortic strain and aortic distensibility = 2 × aortic strain/pulse pressure.

Aortic strain and distensibility were significantly lower, and aortic stiffness index β was significantly higher in the SSc group compared to the control group. While the systolic diameter of the aorta did not differ between study and control groups, the diastolic diameter of the aorta was significantly higher in SSc patients. On the other hand, left ventricular diastolic functions were compromised in the SSc group. Mitral A velocity, E-wave deceleration time and E/Em ratio were increased and mitral E/A ratio, lateral and medial annular Em velocity were significantly decreased in SSc patients.

Our study demonstrated that aortic stiffness is increased and left ventricular diastolic functions are compromised in patients with SSc.

Keywords: Aortic stiffness, echocardiography, heart failure, diastolic; heart atria/pathology; systemic sclerosis.

How to cite this article
Özgül Uçar Elalmış, Hülya Çiçekçioğlu, Ahmet Karagöz, Zeynep Özbalkan Aşlar, Yaşar Karaaslan. Evaluation of aortic elastic properties in patients with systemic sclerosis. Turk Kardiyol Dern Ars. 2014; 42(7): 635-642

Corresponding Author: Ahmet Karagöz, Türkiye
Manuscript Language: English

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