Turk Kardiyol Dern Ars. 2007; 35(5): 273-277
The predictive value of heart rate turbulence for ventricular systolic dysfunction and prognosis in the peri-infarction period
, Ahmet Yılmaz, Okan Turgut, Birhan Yılmaz, Alim Erdem, Can Yontar, İzzet Tandoğan
Cumhuriyet University, Cardiology Department, Sivas
OBJECTIVES This study was conducted to investigate the relationship between heart rate turbulence (HRT) and acute left ventricular systolic dysfunction due to ST-segment elevation acute myocardial infarction (STEMI).
STUDY DESIGN The study included 50 consecutive patients with acute STEMI. All the patients received thrombolytic therapy on admission and underwent transthoracic echocardiographic (TTE) examination at the 24th hour of hospitalization. The patients were divided into two groups according to whether they had decreased or normal left ventricular ejection fraction (LVEF). There were 25 patients (mean age 48±9 years; LVEF: <55%) in group 1, and 25 patients (mean age 52±9 years; LVEF: ≥55%) in group 2. All the patients underwent 24-hour Holter monitoring after TTE to derive the two HRT parameters, turbulence onset (TO) and turbulence slope (TS), showing early acceleration and late deceleration phases, respectively.
RESULTS Patients in group 1 exhibited a significantly higher mean TO (0.74±1.82% vs -2.35±1.48%, p<0.05) and a significantly lower LVEF (39.1±6.7% vs 57.2±5.3%, p<0.05). The other Holter and echocardiographic variables did not differ significantly between the two groups (p>0.05). An abnormal TO value (≥0%) was found to have sensitivity and specificity of 88% (p<0.05) in predicting acute left ventricular systolic dysfunction (LVEF<55%) during the peri-infarction period of STEMI.
CONCLUSION Impaired TO may be used as a useful predictor of left ventricular systolic dysfunction and poor prognosis in the peri-infarction period of STEMI.
Ekokardiyografi, elektrokardiyografi, kalp hızı; miyokard infarktüsü; prognoz; ventrikül disfonksiyonu, sol; ventrikül erken kompleksi/fizyopatoloji
How to cite this article
Kenan Yalta, Ahmet Yılmaz, Okan Turgut, Birhan Yılmaz, Alim Erdem, Can Yontar, İzzet Tandoğan. The predictive value of heart rate turbulence for ventricular systolic dysfunction and prognosis in the peri-infarction period. Turk Kardiyol Dern Ars. 2007; 35(5): 273-277
Corresponding Author: Kenan Yalta, Türkiye