Turk Kardiyol Dern Ars. 2005; 33(8): 480-487

Aspirin resistance

Erdal Aktürk¹, Ergün Topal¹, Yüksel Aksoy¹

Although aspirin is the most commonly used antithrombotic drug in the treatment of cardiovascular diseases, the appearance of vascular thromboembolic events in some patients receiving aspirin has brought into question its safety and development of aspirin resistance. This article reviews the most current information concerning the cause of aspirin resistance and clinical results and discusses therapeutic implications.

Keywords: Aspirin/pharmacology/therapeutic use/adverse effects; cardiovascular diseases/drug therapy; drug resistance; platelet aggregation/drug effects

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