Neurocardiogenic syncope is the most common cause of syncope. This disorder is considered to be an abnormality in the complex neurocardiovascular interactions responsible for maintaining systemic and cerebral perfusion. Exercise-induced syncope is thought to be one of the rare manifestations of neurocardiogenic syncope. Exercise-induced syncope is reported in highly trained athletes and no other cause for syncope could be assigned to these patients, except abnormal neurocardiogenic reflex. In this case report, we presented a 42-year-old man who experienced a syncopal episode during treadmill exercise testing. All extensive evaluation revealed no identifiable cause of syncope except an abnormal tilt table test.