Turk Kardiyol Dern Ars. 2016; 44(4): 356-356
, Mustafa Gür2
, Hakan Uçar3
, Taner Şeker4
, Murat Çaylı51
Department of Cardiology,, Faculty of Medicine, Kars University; Kars, Turkey2
Adana Numune Training and Research Hospital; Adana, Turkey3
Department of Cardiology, Faculty of Medicine, Biruni University; İstanbul, Turkey4
Department of Cardiology, Osmaniye State Hospital, Osmaniye, Turkey5
Department of Cardiology, Faculty of Medicine, Dicle University; Diyarbakır, Turkey
OBJECTIVE Epicardial fat thickness (EFth) is associated with both left ventricular hypertrophy (LVH) and diastolic dysfunction. However, the effect of EFth on myocardial performance is not known. The aim of this study was to investigate the relationship between EFth and tissue Doppler myocardial per- formance index (TD-MPI), which incorporates both systolic and diastolic left ventricular (LV) function, in newly diagnosed hypertension (HT) patients.
METHODS A total of 314 consecutive, newly diagnosed HT patients were prospectively included (mean age: 51.9±1.7 years). EFth was measured perpendicularly on the free wall of the right ventricle at the end of the systole in 2 echocardiographic views (parasternal short and long axis). Myocardial performance index (MPI) was calculated using tissue Doppler (TD) echocar- diography. Patients were divided into 2 groups according to median TD-MPI levels (TD-MPIlow and TD-MPIhigh).
RESULTS EFth values of the TD-MPIhigh group were higher than those of the TD-MPIlow group (p<0.05). Patients in the TD-MPIhigh group also had higher age, body mass index, systolic blood pressure (SBP), diastolic blood pressure (DBP), left ventricular mass index (LVMI), E/A ratio, and aortic dis- tensibility, compared with the TD-MPIlow group (p<0.05 for all). Multivariate linear regression analysis showed that TD-MPI was independently associated with age (β=0.089, p=0.012), LVMI (β=0.090, p=0.05), E/A (β=-0.118, p=0.005), and EFth (β=0.432, p<0.001).
CONCLUSION TD-MPI was independently associated with EFth in patients with newly diagnosed HT. EFth may be used as a predictor of impaired LV global functions in patients with normal left ventricular ejection fraction (LVEF) and newly diagnosed HT.
Epicardial fat thickness, hypertension, hypertrophy, myocardial performance index.
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Sorumlu Yazar: Hakan Uçar, Türkiye