ISSN 1016-5169 | E-ISSN 1308-4488
Archives of the Turkish Society of Cardiology
Amrinone in the Treatment of Heart Failure: Comparison with Dopamine [Turk Kardiyol Dern Ars]
Turk Kardiyol Dern Ars. 1990; 18(3): 186-189

Amrinone in the Treatment of Heart Failure: Comparison with Dopamine

Zuhal AYKAÇ1, Ercüment KOPMAN1, Yıldırım SEYİTHANOĞLU1, Aydın ÇAĞIL1

The hemodynamic effects of a new inotropic agent amrinone (phoshodiesterase III. İnhibitor), is compared with the hemodynamic effects of dopamine. Eight patients with cardiac failure (NYHA class 3-4) were studied with oximetric Swan-Ganz catheters. Significant rises in mean arterial pressure (MAP), heart rate (HR), pulmonary artery pressure (PAP), pulmonary capillary wedge pressure (PCWP), pulmonary vascular resistance (PVR) and cardiacc index (CD) were obtained with dopamine. However, amrinone caused significant fall in PAP, PCWP and systemic vascular resistance (SVR), while it led to no significant differences in HR, MAP and PVR.

Keywords: inotropic agents, phosphodiesterase inhibitor is amrinone, dopamine

How to cite this article
Zuhal AYKAÇ, Ercüment KOPMAN, Yıldırım SEYİTHANOĞLU, Aydın ÇAĞIL. Amrinone in the Treatment of Heart Failure: Comparison with Dopamine. Turk Kardiyol Dern Ars. 1990; 18(3): 186-189
Manuscript Language: Turkish


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