ISSN 1016-5169 | E-ISSN 1308-4488
Archives of the Turkish Society of Cardiology
Increased level of red cell distribution width is associated with poor coronary collateral circulation in patients with stable coronary artery disease [Turk Kardiyol Dern Ars]
Turk Kardiyol Dern Ars. 2015; 43(2): 123-130 | DOI: 10.5543/tkda.2015.24819

Increased level of red cell distribution width is associated with poor coronary collateral circulation in patients with stable coronary artery disease

İrfan Şahin1, Ahmet Karabulut2, Adnan Kaya3, Barış Güngör3, Ilhan Ilker Avcı1, Ertugrul Okuyan1, Mehmet Mustafa Can3, Serhat Sığırcı1, Burak Ayça1, Mustafa Hakan Dinckal1
1Department of Cardiology, Bagcilar Training And Research Hospital, Istanbul, Turkey
2Department of Cardiology, Istanbul Medicine Hospital, Istanbul, Turkey
3Department of Cardiology, Siyami Ersek Thoracic And Cardiovascular Surgery Center, Training And Research Hospital, Istanbul, Turkey


OBJECTIVES
Previous studies have shown the association between various hematological parameters and cardiovascular diseases, and their prognostic value. In this study, we compared red cell distribution width (RDW), neutrophil lymphocyte ratio (NLR) and mean platelet volume (MPV) measurements among patients with poor coronary collateral circulation (CCC) and well-developed CCC.

STUDY DESIGN
326 patients with stable coronary artery disease (CAD) were evaluated retrospectively. CCC was graded by using the Rentrop classification. The poor CCC group included patients with Rentrop 0-1 CCC, and the good CCC group included Rentrop 2-3 CCC.

RESULTS
There were 171 subjects (84% male; mean age 56.6±10.4 years) in the poor CCC group, and 155 subjects (89% male; mean age 57.6±9.7 years) in the good CCC group. The total number of vessels with >95% stenosis (1.1±0.5 vs. 1.0±0.4; p=0.64) and Gensini scores (84.4±38.8 vs. 83.3±37.4; p=0.83) was not higher in the poor CCC group compared to the good CCC group. RDW was significantly higher in the poor CCC group compared to the good CCC group (14.19±1.36% vs. 13.89±1.19%; p=0.04). In multivariate logistic regression analysis, elevated levels of RDW and LDL were found to be independent predictors of poor CCC (OR 1.73, 95% CI: 1.30-2.29, p=0.01 and OR 1.01 95% CI 1.002-1.02; p=0.02, respectively).

CONCLUSION
In the present study, poor CCC was found to be independently correlated with RDW, but not with any other hematological parameters in patients with stable CAD.

Keywords: Collateral circulation, coronary artery disease; red cell distribution width

How to cite this article
İrfan Şahin, Ahmet Karabulut, Adnan Kaya, Barış Güngör, Ilhan Ilker Avcı, Ertugrul Okuyan, Mehmet Mustafa Can, Serhat Sığırcı, Burak Ayça, Mustafa Hakan Dinckal. Increased level of red cell distribution width is associated with poor coronary collateral circulation in patients with stable coronary artery disease. Turk Kardiyol Dern Ars. 2015; 43(2): 123-130

Corresponding Author: İrfan Şahin, Türkiye
Manuscript Language: English


Journal Metrics

Journal Citation Indicator: 0.18
CiteScore: 1.1
Source Normalized Impact
per Paper:
0.22
SCImago Journal Rank: 0.348

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