ISSN 1016-5169 | E-ISSN 1308-4488
Archives of the Turkish Society of Cardiology
Case Reports Prostacyclin Usage in Treatment of Acute Right Heart Failure During Mitral Valve Replacement [Turk Kardiyol Dern Ars]
Turk Kardiyol Dern Ars. 1996; 24(3): 186-189

Case Reports Prostacyclin Usage in Treatment of Acute Right Heart Failure During Mitral Valve Replacement

Deniz Süha KÜÇÜKAKSU1, Şeref A. KÜÇÜKER1, Salih Fehmi KATIRCIOĞLU1, Erol ŞENER1, Oğuz TAŞDEMİR1, Kemal BAYAZIT1

In three patients with pulmonary hypertension (mean pulmonary artery pressure was 91±4.5/52±9.6 mmHg) acute right heart failure developed after mitral valve replacement. Because weaning from cardiopulmonary bypass was unsuccessful despite various medical and mechanical (intraaortic balloon) supports used, prostacyclin (Flolan, 5-20 nanogram/kg/min) was begun intravenously. We observed improvement of right ventricular contraction and decrease of mean pulmonary artery pressures to 52±2/29±6.2 mmHg (p<0.05) associated with decrease of mean pulmonary vascular resistance to 62±6 from 340±28 dyn.sec./cm5 (p<0.05) within first 30 minutes after prostacylin administration. Then,all patients were weaned from cardiopulmonary bypass. A complication related to prostacyclin was not detected. We concluded that combination of prostacyclin with inotropic drugs is an effective therapy to improve the detoriated hemodynamics of these patients.


How to cite this article
Deniz Süha KÜÇÜKAKSU, Şeref A. KÜÇÜKER, Salih Fehmi KATIRCIOĞLU, Erol ŞENER, Oğuz TAŞDEMİR, Kemal BAYAZIT. Case Reports Prostacyclin Usage in Treatment of Acute Right Heart Failure During Mitral Valve Replacement. Turk Kardiyol Dern Ars. 1996; 24(3): 186-189
Manuscript Language: Turkish


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