Archives of the Turkish Society of Cardiology
Evaluation of the relationship between platelet indices and spontaneous echo contrast in patients with mitral prosthetic heart valves [Turk Kardiyol Dern Ars]
Turk Kardiyol Dern Ars. 2020; 48(2): 127-136 | DOI: 10.5543/tkda.2019.17266

Evaluation of the relationship between platelet indices and spontaneous echo contrast in patients with mitral prosthetic heart valves

Macit Kalçık1, Ahmet Güner2, Emrah Bayam3, Mahmut Yesin4, Semih Kalkan3, Mustafa Ozan Gürsoy5, Sabahattin Gündüz6, Süleyman Karakoyun4, Sinan Cerşit3, Mehmet Özkan7
1Department of Cardiology, Hitit University Faculty of Medicine, Çorum, Turkey
2Department of Cardiology, Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Training and Research Hospital, Istanbul, Turkey
3Department of Cardiology, Koşuyolu Kartal Heart Training and Research Hospital, Istanbul, Turkey
4Department of Cardiology, Faculty of Medicine, Kars Kafkas University, Kars, Turkey
5Department of Cardiology, Izmir Katip Çelebi University, Atatürk Training and Research Hospital, Izmir, Turkey
6Department of Cardiology, VM Medikal Park Pendik Hospital, Istanbul, Turkey
7Division of Health Sciences, Ardahan University, Ardahan, Turkey; Department of Cardiology, Koşuyolu Kartal Heart Training and Research Hospital, Istanbul, Turkey


OBJECTIVE
Spontaneous echo contrast (SEC) is defined as dynamic, smoke-like echoes within the cardiac cavities with a characteristic swirling motion seen on echocardiography. Clinical studies have demonstrated that SEC is a risk factor for left atrial thrombus formation and an important indicator for potential systemic embolism. Platelet indices have been associated with the presence of SEC in patients with mitral stenosis. The aim of this study was to investigate the relationship between platelet indices and SEC in patients with prosthetic heart valves.

METHODS
A total of 89 patients [female: 38 (42.4%); median age: 52 years (range: 36-67 years)] with SEC formation in the left atrium, and 257 control subjects [female: 123 (47.5%); median age: 56 years (range: 45-65 years)] without SEC formation were enrolled. All of the patients were evaluated by using transthoracic and transesophageal echocardiography. Laboratory tests including complete blood count and biochemical parameters were analyzed.

RESULTS
Patients with SEC formation had more frequent atrial fibrillation, higher left atrial diameter (LAD) and lower left ventriular ejection fraction values. Platelet indices including platelet count, platelet distribution width, mean platelet volume, and plateletcrit did not differ between the groups. Increased LAD was detected as the only independent predictor of SEC development.

CONCLUSION
Platelet indices were not found to be associated with the presence of SEC formation in the left atrium among patients with mitral prosthetic valves. Therefore, the use of platelet indices alongside known echocardiographic and clinical risk factors to predict SEC development in patients with a mitral prosthesis is debatable.

Keywords: Echocardiography, platelet; spontaneous echo contrast; transesophageal echocardiography.

How to cite this article
Macit Kalçık, Ahmet Güner, Emrah Bayam, Mahmut Yesin, Semih Kalkan, Mustafa Ozan Gürsoy, Sabahattin Gündüz, Süleyman Karakoyun, Sinan Cerşit, Mehmet Özkan. Evaluation of the relationship between platelet indices and spontaneous echo contrast in patients with mitral prosthetic heart valves. Turk Kardiyol Dern Ars. 2020; 48(2): 127-136

Corresponding Author: Macit Kalçık, Türkiye
© Copyright 2020 Archives of the Turkish Society of Cardiology
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