ISSN 1016-5169 | E-ISSN 1308-4488
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A Recent Development in Invasive Cardiology: Fractional Flow Reserve (FFR) [Turk Kardiyol Dern Ars]
Turk Kardiyol Dern Ars. 2000; 28(5): 321-326

A Recent Development in Invasive Cardiology: Fractional Flow Reserve (FFR)

Y.Oğuz CAYMAZ1, Ahmet OKTAY1

Even quantitative coronary angiography has limitations in defining the physiologic importance of a given coronary artery lesion. The usual non-invasive stress tests (exercise stress test, myocardial perfusion scintigraphy, stress echocardiography) may have the same limitations regarding either diagnostic value or time and money consumption due to the performance in a different location other than the angiography laboratory. Recently developed fractional flow reserve (FFR) method, as an invasive tool, seems to have solutions for both. By definition, FFR is the ratio of post- and pre-lesional pressures measured at the point of maximal hyperemia induced by intracoronary infusion of pharmachologic agents. Distal pressures can be easily obtained with the help of a microtransducer mounted on usual angioplasty guidewires. Upto-date there are numerous publications confirming the application of FFR method which includes defining the physiologic İnıportance of coronary lesions; postponing the planned coronary intervention on the basis of FFR measurements; guidance for optimal PTCA or coronary stent applications. The limitations, in other words the field for new investigations, of the method are the presence of systemic or local myocardial diseases that may effect the microvascular bed of the related myocardial region. In this review the theoretical basis, application technique in the cath-lab, well-defined indications and limitations of the FFR method are discussed.

Keywords: fractional flow reserve, coronary artery disease, coronary ballon angioplasty, ischemia, acute myocardial infarction

How to cite this article
Y.Oğuz CAYMAZ, Ahmet OKTAY. A Recent Development in Invasive Cardiology: Fractional Flow Reserve (FFR). Turk Kardiyol Dern Ars. 2000; 28(5): 321-326
Manuscript Language: Turkish


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