Evaluation of left ventricular regional systolic functions in patients with coronary artery disease by two-dimensional strain imaging: a velocity vector imaging study) [Turk Kardiyol Dern Ars]
Turk Kardiyol Dern Ars. 2011; 39(2): 93-104 | DOI: 10.5543/tkda.2011.01065

Evaluation of left ventricular regional systolic functions in patients with coronary artery disease by two-dimensional strain imaging: a velocity vector imaging study)

Yelda Tayyareci1, Özlem Yıldırımtürk1, Selen Yurdakul1, Vedat Aytekin2, İc. Cemşid Demiroğlu1, Saide Aytekin2
1Florence Nightingale Hospital, Cardiology Division, Istanbul, Turkey
2Istanbul Bilim University, Department of Cardiology, Istanbul, Turkey


OBJECTIVES
The aim of the study was to assess left ventricular (LV) regional systolic functions in coronary artery disease (CAD) using a novel strain imaging method, namely, velocity vector imaging (VVI).

STUDY DESIGN
The study included 69 patients (51 men, 18 women; mean age 52.9±10.3 years) with CAD and 30 healthy volunteers (22 men, 8 women; mean age 58.1±13.8 years). Thirty-three patients had previous myocardial infarction (MI). In all the patients, LV wall motions were analyzed as akinetic, hypokinetic, or normokinetic using the 16-segment model of the American Heart Association. In addition, LV peak systolic strain, strain rate (SRs), and segmental ejection fraction (SEF) of all the segments were calculated by using VVI.

RESULTS
Patients with MI had significantly lower mean peak systolic strain, SRs, and SEF compared to patients without MI and controls (p=0.0001). The presence of multivessel disease was accompanied by significantly decreased peak systolic strain (p=0.04), SRs (p=0.02), and SEF (p=0.0001). Myocardial segments affected by subtotal/total occlusion (≥99%) had lower peak systolic strain (p=0.02), SRs (p=0.001), and SEF (p=0.0001) values compared to segments with less severe occlusion. In segmental analysis, longitudinal deformation was most significant in akinetic segments (p=0.0001), but hypokinetic and normokinetic segments also differed significantly with respect to deformation (for strain, p=0.01; for SRs and SEF, p=0.0001). Moreover, deformation in the normokinetic segments was more significant than normal segments of the controls (for strain, p=0.02; for SRs and SEF, p=0.0001).

CONCLUSION
Velocity vector imaging allows regional deformation analysis for quantitative assessment of regional LV systolic functions; this technique may be more reliable than conventional echocardiography in determining wall motion abnormalities.

Keywords: Coronary angiography, coronary artery disease; coronary occlusion; echocardiography/methods; heart failure, systolic/diagnosis; myocardial infarction; ventricular dysfunction, left

How to cite this article
Yelda Tayyareci, Özlem Yıldırımtürk, Selen Yurdakul, Vedat Aytekin, İc. Cemşid Demiroğlu, Saide Aytekin. Evaluation of left ventricular regional systolic functions in patients with coronary artery disease by two-dimensional strain imaging: a velocity vector imaging study). Turk Kardiyol Dern Ars. 2011; 39(2): 93-104

Corresponding Author: Saide Aytekin, Türkiye
© Copyright 2019 Archives of the Turkish Society of Cardiology
LookUs & Online Makale