ISSN 1016-5169 | E-ISSN 1308-4488
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Massive pericardial effusion as the primary manifestation of high-grade malignant lymphoma [Turk Kardiyol Dern Ars]
Turk Kardiyol Dern Ars. 2009; 37(8): 578-579

Massive pericardial effusion as the primary manifestation of high-grade malignant lymphoma

Serkan Çay1, Akif Durak1, Sinan Aydoğdu1, Nesrin Turhan2
1Department of Cardiology, Türkiye Yüksek İhtisas Heart Education and Research Hospital, Ankara
2Departments of Pathology, Türkiye Yüksek İhtisas Heart-Education and Research Hospital

Pericardial effusion might be the first presentation of various pathologies including malignant tumors. Massive pericardial effusion as the primary manifestation of high-grade malignant lymphoma is a very rare condition. A 53-year-old woman presented with progressive dyspnea of one week history. Physical examination showed venous distention of the neck veins and diminished heart sounds. The chest X-ray demonstrated increased cardiothoracic index. Transthoracic and transesophageal echocardiographic examinations showed massive pericardial effusion without any other pathology. Hematologic and biochemical tests showed only anemia. The patient underwent pericardiocentesis. Pericardial adenosine deaminase test and cultures were negative. Cytopathologic examination of the fluid showed huge lymphocytes and highly atypical lymphoid cells consistent with high-grade malignant lymphoma (non-Hodgkin’s lymphoma). Immunohistochemical analysis showed positivity for leukocyte common antigen. No other primary origin could be determined.

Keywords: Lymphoma, non-Hodgkin/diagnosis/pathology, pericardial effusion.

How to cite this article
Serkan Çay, Akif Durak, Sinan Aydoğdu, Nesrin Turhan. Massive pericardial effusion as the primary manifestation of high-grade malignant lymphoma. Turk Kardiyol Dern Ars. 2009; 37(8): 578-579

Corresponding Author: Serkan Çay, Türkiye
Manuscript Language: English


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