Early- and mid-term effects of percutaneous mitral balloon valvuloplasty on left atrial mechanical functions in mitral stenosis [Turk Kardiyol Dern Ars]
Turk Kardiyol Dern Ars. 2014; 42(6): 517-523 | DOI: 10.5543/tkda.2014.09147

Early- and mid-term effects of percutaneous mitral balloon valvuloplasty on left atrial mechanical functions in mitral stenosis

Sinan İnci1, Mustafa Kemal Erol2, Muhammet Hakan Taş3, Eftal Murat Bakırcı3, Hikmet Hamur3, Şule Karakelleoğlu3
1Department of Cardiology, Aksaray State Hospital, Aksaray
2Department of Cardiology, Kemerburgaz University Faculty of Medicine, İstanbul
3Department of Cardiology, Ataturk University Faculty of Medicine, Erzurum


OBJECTIVES
The aim of the study was to evaluate left atrial (LA) mechanical functions in MS before and after percutaneous mitral balloon valvuloplasty (PMBV) and to follow it up in short- and mid-term.

STUDY DESIGN
We carried out a prospective study of 49 patients with critical mitral stenosis (MS) who had normal sinus rhythm. LA mechanical functions were evaluated before and 24-48 h, 3 months, and 1 year after PMBV, which included LA passive emptying volume (LAPEV), LA active emptying volume (LAAEV), LA total emptying volume (LATEV), LA passive emptying fraction (LAPEF), LA active emptying fraction (LAAEF), LA total emptying fraction (LATEF), and conduit volume.

RESULTS
The transthoracic echocardiography parameters of the MS patients before and 24-48 h, 3 months, and 1 year after PMBV were as follows: (a) mitral valve area 1.1 cm² (0.9-1.6); 2.2 cm² (1.8-2.8) (p<0.001); 2.2 cm² (1.7-2.9) (NS); 2.1 cm² (1.8-2.7) (p<0.001); (b) LAPEV 13 ml/m² (9-27); 11 ml/m² (8-19) (p<0.001); 10 ml/m² (7-19) (p<0.001); 10 ml/m² (6-18) (p<0.001); (c) LATEV 26 ml/m² (19-50); 21 ml/m² (16- 40) (p<0.001); 20 ml/m² (15-36) (p<0.001); 19 ml/m² (15-34) (p<0.001); (d) Conduit volume 30 ml/m² (22-44); 33 ml/m² (26- 46) (p<0.001); 34 ml/m² (30-42) (p<0.001); 36 ml/m² (31-42) (p<0.001), respectively. However, LAAEV, LAPEF, LAAEF, and LATEF were not altered after PMBV.

CONCLUSION
The findings of this study demonstrated an improvement of LA mechanical functions, which continued to improve for 1 year, after successful treatment of MS by PMBV.

Keywords: Atrial function, left, balloon valvuloplasty, cardiac catheterization/ methods; mitral valve stenosis/therapy.

How to cite this article
Sinan İnci, Mustafa Kemal Erol, Muhammet Hakan Taş, Eftal Murat Bakırcı, Hikmet Hamur, Şule Karakelleoğlu. Early- and mid-term effects of percutaneous mitral balloon valvuloplasty on left atrial mechanical functions in mitral stenosis. Turk Kardiyol Dern Ars. 2014; 42(6): 517-523

Corresponding Author: Sinan İnci, Türkiye
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