Turk Kardiyol Dern Ars. Ahead of Print: TKDA-24804 | DOI: 10.5543/tkda.2019.24804
Rationale and Design of the Myocardial Infarction with Non-obstructive Coronary Arteries in Turkish Population (MINOCA-TR) Study
Uğur Önsel Türk1
, Mehdi Zoghi2
, Emin Alioglu1
, Oktay Ergene31
KardiyoRitm Heart Center, Izmir, Turkey2
Ege University School of Medicine, Dept. of Cardiology, Izmir, Turkey3
Dokuz Eylul University School of Medicine, Dept. of Cardiology, Izmir, Turkey
Myocardial infarction (MI) with non-obstructive coronary arteries (MINOCA) is new term which defining the syndrome of clinical evidence of MIs occurred in the absence obstructive coronary artery disease. Regarding to possible huge number of these patients, effective diagnostic and therapeutic should be obtained. Documentation of demographics and diagnostic methods which have used already are first steps of this process. The purpose of the study is documentation of prevalence, demographics, possible etiologic causes as well as inpatient and one year prognosis of MINOCA in Turkish Population.
The study is national, multi-center, prospective, observational study and 1028 consecutive MI (according to third universal MI definition) patients who undergoing diagnostic angiography will be enrolled. After the initial screening/enrolment visit, follow-up visits will occur at the time of hospital discharge for overall study population. Patients who diagnosed as MINOCA will be followed with three prospective office or telephone visits as part of conjoint prospective MINOCA registry. The overall follow-up period will be 1 year, and will conclude with 3rd patient visit.
Demographics, clinical characteristics, management strategies, and inpatient prognostic indicators will be documented in cross-sectional part of the registry. Additional diagnostic, therapeutic strategies and prognostic relevance will also surveyed with 12 month of prospective part. The results will inform future diagnostic and therapeutic strategies and enhance understanding of public health aspects of this condition. These data will highlight the national burden of the disease in medical and public perspective and be stimulate the future researches which focusing on the MINOCA population.
Demographics, Myocardial Infarction, Non-obstructive coronaries, Prognosis
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Corresponding Author: Uğur Önsel Türk, Türkiye