Archives of the Turkish Society of Cardiology
Data on prevalence of hypertension and blood pressure in Turkey: Systematic review, meta-analysis and meta-regression of epidemiological studies on cardiovascular risk factors [Turk Kardiyol Dern Ars]
Turk Kardiyol Dern Ars. 2018; 46(7): 525-545 | DOI: 10.5543/tkda.2018.15679

Data on prevalence of hypertension and blood pressure in Turkey: Systematic review, meta-analysis and meta-regression of epidemiological studies on cardiovascular risk factors

Mustafa Kılıçkap1, Cem Barçın2, Hüseyin Göksülük1, Doruk Karaaslan3, Necla Özer4, Meral Kayıkçıoğlu5, Dilek Ural6, Mehmet Birhan Yılmaz7, Adnan Abacı8, Mustafa Arıcı9, Bülent Altun9, Lale Tokgözoğlu4, Mahmut Şahin10
1Department of Cardiology, Ankara University Faculty of Medicine, Ankara, Turkey
2Department of Cardiology, Health Sciences University Gülhane Training and Research Hospital, Ankara, Turkey
3Koç University Faculty of Medicine, İstanbul, Turkey
4Department of Cardiology, Hacettepe University Faculty of Medicine, Ankara, Turkey
5Department of Cardiology, Ege University Faculty of Medicine, İzmir, Turkey
6Department of Cardiology, Koç University Faculty of Medicine, İstanbul, Turkey
7Department of Cardiology, Cumhuriyet University Faculty of Medicine, Sivas, Turkey
8Department of Cardiology, Gazi University Faculty of Medicine, Ankara, Turkey
9Department of Nephrology, Hacettepe University Faculty of Medicine, Ankara, Turkey
10Department of Cardiology, Ondokuz Mayıs University Faculty of Medicine, Samsun, Turkey


OBJECTIVE
Cardiovascular risc factors may show significant changes over the years. A systematic review and meta-analysis of epidemiological studies conducted in Turkey was performed to assess the latest profile and temporal changes in cardiovascular risk factors. Presented here are the data on hypertension (HT) and blood pressure (BP).

METHODS
Ovid Medline, the Web of Science Core Collection, and the Turkish Academic Network and Information Center (ULAKBIM) were searched for epidemiological studies conducted in Turkey during the last 15 years. In addition, the web pages of the Ministry of Health, the Turkish Statistical Institute, and associations of cardiology, nephrology, and endocrinology were searched for appropriate studies. Regional studies were excluded. The studies included were assessed with a bias score developed by our team, then categorized as having a low risk or a high risk of bias. The crude values of HT prevalence and BP were pooled using a random effects model. Meta-regression was performed to explain heterogeneity and to assess temporal changes.

RESULTS
The agreement between the 2 authors on the selection and bias scoring of the studies was perfect (Kappa ≥0.95). There were 7 (n=73218) studies providing HT prevalence data, and 8 (n=75879) studies with BP data. The heterogeneity between the studies was high. Meta-analysis of the studies with a low risk of bias indicated that the crude prevalence of HT is higher in women, but that BP levels were similar in both sexes. The HT prevalence and BP value decreased between 2003 and 2012; however, the number of hypertensives stabilized at approximately 15 million, and the number of uncontrolled hypertensives, despite some decrease, was around 11 million.

CONCLUSION
Despite some improvement, HT is still an important public health problem in Turkey.

Keywords: Epidemiology, hypertension; blood pressure; meta-analysis; meta-regression; prevalence.

How to cite this article
Mustafa Kılıçkap, Cem Barçın, Hüseyin Göksülük, Doruk Karaaslan, Necla Özer, Meral Kayıkçıoğlu, Dilek Ural, Mehmet Birhan Yılmaz, Adnan Abacı, Mustafa Arıcı, Bülent Altun, Lale Tokgözoğlu, Mahmut Şahin. Data on prevalence of hypertension and blood pressure in Turkey: Systematic review, meta-analysis and meta-regression of epidemiological studies on cardiovascular risk factors. Turk Kardiyol Dern Ars. 2018; 46(7): 525-545

Corresponding Author: Mustafa Kılıçkap, Türkiye
© Copyright 2018 Archives of the Turkish Society of Cardiology
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