Relationship Between QT Dispersion and Coronary Angiography Findings in Coronary Artery Disease [Turk Kardiyol Dern Ars]
Turk Kardiyol Dern Ars. 2000; 28(8): 489-494

Relationship Between QT Dispersion and Coronary Angiography Findings in Coronary Artery Disease

Mehmet KANADAŞI1, Şenol DEMİRCAN1, Mesut DEMİR1, Y.Ferit AKGÜL2, Esmeray ACARTÜRK1
1
2

The aim of this study was to evaluate the relationship between severity of coronary artery lesions, left ventricular wall motion abnormalities and QT dispersion in patients with ischemic heart disease. Two hundred and eighteen patients ( 144 males, 74 females), age between 33-73 years (mean: 52.9±9.9) were included in the study. All patients had coronary angiography because of suspected coronary artery disease. Standard electrocardiogram (ECG) with simultaneous 12 lead acquisition were recorded at 50 mm/sec. QT interval was manually measured from the onset of QT till the end of T wave at each lead. The QT dispersion was defined as the diffe rence between the maximum and minimum QT interval, occurring in any of the electrocardiographic leads. Using the Bazett' s formula we corrected QT (QTc) and using this data, found out the corrected QT dispersion (QTcd). After coronary angiography, we divided the subgroups according to their coronary lesions and left ventricular wall motion abnormalities. The patients having 50% or more stenosis were taken as the group with coronary lesions. Wall motion score (WMS) was calculated and recorded for each patient considering contractility degree of wall segments on left ventriculography. QTcd was found to be significantly higher in patients with left anterior descending (LAD) artery stenosis in the group with one coronary artery lesion compared with the group with normal coronary arteries (p<0.001). QTcd was significantly higher in the groups with 2 and 3 coronary lesions compared to the normal group (p<0.001). We did not find a significant difference between circumflex (CX) and right coronary artery (RCA) lesions together or isolated CX and RCA. Patients with coronary artery disease were divided into two subgroups either having left ventricular wall motion abnormalities or not. We also compared the differences of QTd between these groups. QTcd was found to be significantly higher in the group with wall motion abnormalities. Our study shows that QTcd is increased significantly in LAD artery lesions and/or coronary pathologies accompanying LAD artery lesions, especially in patients with left ventricular wall motion abnormalities due to ischemia or necrosis.

Keywords: Coronary artery disease, coronary angiography, QT dispersion

How to cite this article
Mehmet KANADAŞI, Şenol DEMİRCAN, Mesut DEMİR, Y.Ferit AKGÜL, Esmeray ACARTÜRK. Relationship Between QT Dispersion and Coronary Angiography Findings in Coronary Artery Disease. Turk Kardiyol Dern Ars. 2000; 28(8): 489-494
© Copyright 2019 Archives of the Turkish Society of Cardiology
LookUs & Online Makale