Safety of radial coronary angiography with uninterrupted direct-acting oral anticoagulant treatment [Turk Kardiyol Dern Ars]
Turk Kardiyol Dern Ars. 2019; 47(1): 4-9 | DOI: 10.5543/tkda.2018.82830

Safety of radial coronary angiography with uninterrupted direct-acting oral anticoagulant treatment

Tuğba Kemaloğlu Öz1, Tayfun Gürol1, Nedim Umutay Sarıgül2, Utku Arslan1, Maryam Kobegenova1, Alper Aydın1, Özer Soylu1, Bahadir Dağdeviren1
1Department of Cardiology, Bahçeşehir University Faculty of Medicine, İstanbul, Turkey
2Department of Cardiology, Kardio Bremen, Bremen, Germany


OBJECTIVE
It is not known whether direct-acting oral anticoagulants (DOACs), such as dabigatran, apixaban, and rivaroxaban increase the risk of bleeding complications during or after coronary catheterization. The aim of this study was to investigate the safety of uninterrupted DOAC treatment during diagnostic radial coronary angiography (CAG).

METHODS
This study included 160 patients who underwent diagnostic radial cardiac catheterization. The 60 patients in the group who were using a DOAC (apixaban, rivaroxaban, or dabigatran) were enrolled in a Group A. Post-procedure results from patients in Group A were compared with those of an age- and sex-matched control group (Group B) that included 100 patients who underwent radial CAG who did not use a DOAC.

RESULTS
There was no significant difference in the procedure and compression times, creatinine level, or presence of hypertension, diabetes mellitus, smoking, alcohol use, vascular disease, or congestive heart failure between the 2 groups. During the 1 -month follow-up period, only 1 radial occlusion was registered in the control group (Group B). There was no case of a large hematoma (>5 cm or extending to the forearm), dissection, fistula, perforation, or compartment syndrome. Hematomas smaller than 5 cm were seen in 2 patients (1 in each group). No thrombotic events were observed during follow-up examinations.

CONCLUSION
Performing radial CAG with uninterrupted DOAC treatment appears to carry no risk of increased early or short-term complications. The simple, uninterrupted DOAC strategy is comfortable, easy, and safe.

Keywords: Anticoagulants, apixaban, coronary angiography; dabigatran; radial artery; rivaroxaban.

How to cite this article
Tuğba Kemaloğlu Öz, Tayfun Gürol, Nedim Umutay Sarıgül, Utku Arslan, Maryam Kobegenova, Alper Aydın, Özer Soylu, Bahadir Dağdeviren. Safety of radial coronary angiography with uninterrupted direct-acting oral anticoagulant treatment. Turk Kardiyol Dern Ars. 2019; 47(1): 4-9

Corresponding Author: Tuğba Kemaloğlu Öz, Türkiye
© Copyright 2019 Archives of the Turkish Society of Cardiology
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