Turk Kardiyol Dern Ars. Ahead of Print: TKDA-80027 | DOI: 10.5543/tkda.2019.80027
The impact of the New Pulmonary Hypertension Definition of the World Symposia on Pulmonary Hypertension on The Prevalence of Pre-capillery Pulmonary Hypertension
Umit Yasar Sinan
, Özge Çetinarslan
, Alev Arat-Özkan
, Murat Kazim Ersanli
, MEHMET SERDAR KÜÇÜKOGLU
Department of Cardiology, Istanbul University Cerrahpasa Institute of Cardiology, Istanbul, Turkey
INTRODUCTION Since 1st World Symposia on Pulmonary Hypertension (Geneva 1973), pulmonary hypertension (PH) has been defined as mean pulmonary artery pressure ≥ 25 mmHg measured by right heart catheterization in the supine position at rest. On 6th WSPH congress (Nice 2018), a new proposal defining pre-capillary PH as PAPm >20 mmHg, pulmonary artery wedge pressure <15 mmHg and pulmonary vascular resistance >3 Wood unit was suggested. We aimed to investigate the impact of the new definition of PH on the number of pre-capillary PH patients.
METHODS We screened the RHC performed with various clinical indications between 2017 and 2018. Both 2015 ESC/ERS and 6th WSPH congress PH definition were used to define PH patients.
RESULTS Fifty-eight RHC were performed in our hospital in one-year period. Most of them were performed with a suspicion of PH (N: 52). The remaining (N: 6) were performed with indications of valvular heart disease and left heart disease. There were 40 females (69%) and 18 males (31%) patients. The mean age was 53.3 ± 16.6 years old. On RHC, the PAPm was 36.4 ± 16.4 mmHg, PCWP was 12.6 ± 3.9 mmHg and PVR was 4.9 ± 4.4 WU. Forty-three of 58 patients (74.1%) were classified as pre-capillary PH according to 2015 ESC/ERS PH guideline, whereas 50 of 58 patients (86.2%) had pre-capillary PH according to 6th WSPH congress.
CONCLUSION Our study revealed that the impact of the new definition of PH on the number of pre-capillary PH patients identified was greater than the predicted <%10.
World Symposia on Pulmonary Hypertension, pre-capillary PH, hemodynamic, right heart catheterization
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Corresponding Author: Umit Yasar Sinan, Türkiye