Do we pay proper attention to triglyceride levels in coronary artery disease? [Turk Kardiyol Dern Ars]
Turk Kardiyol Dern Ars. 2006; 34(4): 218-222

Do we pay proper attention to triglyceride levels in coronary artery disease?

Meral Kayıkçıoğlu1, Muge Ildızlı1, Murat Olukman2, Can Hasdemir1, Oguz Yavuzgil1, Levent Can1, Cemil Gürgün1, Hakan Kültürsay1, İnan Soydan1
1Ege University Medical School Department Of Cardiology
2Ege University Medical School Department Of Pharmacology


OBJECTIVES
Epidemiological studies have demonstrated that elevated triglyceride levels increase the risk for coronary artery disease (CAD). This study sought to evaluate the approach to triglyceride levels in patients with CAD in the cardiology department of a tertiary medical center.

STUDY DESIGN
The study consisted of 100 consecutive patients (79 males, 21 females; mean age 58±10 years) who were admitted to the cardiology department of a university hospital with angina pectoris and were found to have CAD by elective coronary angiography. Data were obtained from hospital records. Lipid profiles of the patients and management strategies were assessed.

RESULTS
Hyperlipidemia was detected in 66%. The mean total cholesterol, triglyceride, high- and low-density lipoprotein cholesterol levels were 203±44 mg/dl, 195±106 mg/dl, 43±11 mg/dl, and 124±38 mg/dl, respectively. On admission, none of the patients were receiving fibrates, and 31% were on statin treatment, which increased to 65% on discharge. In 10 patients, triglyceride levels were not determined at all. According to the Adult Treatment Panel III (ATP III), triglyceride levels were normal (<150 mg/dl) in 29 patients (32.2%). Twenty-five patients (27.8%) had a high-normal triglyceride level (150 to 199 mg/dl), of which statin treatment was instituted in 14 patients on discharge. Thirty-five patients (38.9%) with a high triglyceride level (200 to 499 mg/dl) had hypertriglyceridemia as the most prominent lipid profile; of these, statin treatment was instituted in 27 patients and fibrates were prescribed to three patients.

CONCLUSION
Our data show that triglyceride levels do not receive proper attention and that fibrates are underused in the treatment of hypertriglyceridemia in CAD. Considering high triglyceride levels, awareness of physicians for hypertriglyceridemia and its treatment should be enhanced.

Keywords: Antilipemic agents/therapeutic use, coronary disease, hypertriglyceridemia/complications/therapy, triglycerides.

How to cite this article
Meral Kayıkçıoğlu, Muge Ildızlı, Murat Olukman, Can Hasdemir, Oguz Yavuzgil, Levent Can, Cemil Gürgün, Hakan Kültürsay, İnan Soydan. Do we pay proper attention to triglyceride levels in coronary artery disease?. Turk Kardiyol Dern Ars. 2006; 34(4): 218-222

Corresponding Author: Meral Kayıkçıoğlu, Türkiye
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