Data on prevalence of metabolic syndrome in Turkey: Systematic review, meta-analysis and meta-regression of epidemiological studies on cardiovascular risk factors [Turk Kardiyol Dern Ars]
Turk Kardiyol Dern Ars. 2018; 46(7): 591-601 | DOI: 10.5543/tkda.2018.00878

Data on prevalence of metabolic syndrome in Turkey: Systematic review, meta-analysis and meta-regression of epidemiological studies on cardiovascular risk factors

Adnan Abacı1, Mustafa Kılıçkap2, Hüseyin Göksülük2, Doruk Karaaslan3, Cem Barçın4, Meral Kayıkçıoğlu5, Necla Özer6, Mehmet Birhan Yılmaz7, Mahmut Şahin8, Lale Tokgözoğlu6
1Department of Cardiology, Gazi University, Faculty of Medicine, Ankara, Turkey
2Department of Cardiology, Faculty of Medicine, Ankara University, Ankara, Turkey
3Koç University Faculty of Medicine, İstanbul
4Department of Cardiology, Gülhane Training and Research Hospital, Ankara, Turkey
5Department of Cardiology, Ege University Faculty of Medicine, Izmir, Turkey
6Department of Cardiology, Hacettepe University, Faculty of Medicine, Ankara, Turkey
7Department of Cardiology, Cumhuriyet University Faculty of Medicine, Sivas, Turkey
8Department of Cardiology, Ondokuz Mayıs University Faculty of Medicine, Samsun, Turkey


OBJECTIVE
The incidence of metabolic syndrome varies greatly in developed and developing countries. In the last 10 to 15 years, important studies have been performed examining the incidence of metabolic syndrome in Turkey. This article is a meta-analysis of the studies that investigated the incidence of metabolic syndrome this country.

METHODS
Epidemiological studies from the last 15 years that provided information about the incidence of metabolic syndrome in Turkey were screened in the Ovid Medline, the Web of Science Core Collection, and the Turkish Academic Network and Information Center (ULAKBIM) databases. In addition, web pages of the Ministry of Health, the Turkish Statistical Institute, and the associations of the related medical discipilnes were screened for appropriate studies. A bias tool that is developed by our team was used to categorize the included studies as having low- or high risk of bias. A random effects model was used in the meta-analysis. Linear and nonlinear meta-regression analyses were performed to evaluate heterogeneity and temporal variations in prevalence rates.

RESULTS
Four studies (n=34893) were identified that provided information about the status of metabolic syndrome in Turkey using the Adult Treatment Panel III definition. There was excellent interobserver agreement regarding the selection of studies and the scoring of the selected research with respect to bias. The meta-analysis revealed a prevalence of 32.9% (95% confidence interval [CI]: 30.2–35) overall, 38.3% (95% CI: 35.8–40.8) in women, and 26.8% (95% CI: 23.4–30.3) in men. Two studies (n=8568) provided data according to the International Diabetes Federation definition of metabolic syndrome. The random effects model used in the meta-analysis of these studies demonstrated a prevalence of metabolic syndrome of 43.3% (95% CI: 41.9–44.7) overall, 50.4% (95% CI: 49.0–51.9) in women, and 35.4% (95% CI: 32.5–38.5) in men.

CONCLUSION
In Turkey, the incidence of metabolic syndrome is 1 in every 4 men, and 1 in every 3 women. The rate is particularly high among women. Studies designed to prevent the development of metabolic syndrome are needed.

Keywords: Metabolic syndrome, prevalence; Turkey.

How to cite this article
Adnan Abacı, Mustafa Kılıçkap, Hüseyin Göksülük, Doruk Karaaslan, Cem Barçın, Meral Kayıkçıoğlu, Necla Özer, Mehmet Birhan Yılmaz, Mahmut Şahin, Lale Tokgözoğlu. Data on prevalence of metabolic syndrome in Turkey: Systematic review, meta-analysis and meta-regression of epidemiological studies on cardiovascular risk factors. Turk Kardiyol Dern Ars. 2018; 46(7): 591-601

Corresponding Author: Adnan Abacı, Türkiye
© Copyright 2018 Archives of the Turkish Society of Cardiology
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